Du H - Search Results

1

Wolman disease/cholesteryl ester storage disease: efficacy of plant-produced human lysosomal acid lipase in mice.

Du H, Cameron TL, Garger SJ, Pogue GP, Hamm LA, White E, Hanley KM, Grabowski GA. Du H, et al. J Lipid Res. 2008 Aug;49(8):1646-57. doi: 10.1194/jlr.M700482-JLR200. Epub 2008 Apr 15. J Lipid Res. 2008. PMID: 18413899 Free PMC article.

2

Characterization of lysosomal acid lipase by site-directed mutagenesis and heterologous expression.

Sheriff S, Du H, Grabowski GA. Sheriff S, et al. Among authors: du h. J Biol Chem. 1995 Nov 17;270(46):27766-72. doi: 10.1074/jbc.270.46.27766. J Biol Chem. 1995. PMID: 7499245 Free article.

3

Tissue and cellular specific expression of murine lysosomal acid lipase mRNA and protein.

Du H, Witte DP, Grabowski GA. Du H, et al. J Lipid Res. 1996 May;37(5):937-49. J Lipid Res. 1996. PMID: 8725147 Free article.

Our results show that the expression of LAL is regulated in a tissue- and cell-specific manner that corresponds to the pathologic involvement in Wolman disease.-Du, H., D. P. Witte, and G. A. Grabowski. Tissue and cellular specific expression of murine lysosomal aci …

Our results show that the expression of LAL is regulated in a tissue- and cell-specific manner that corresponds to the pathologic involvemen …

4

Mouse lysosomal acid lipase: characterization of the gene and analysis of promoter activity.

Du H, Duanmu M, Rosa LR. Du H, et al. Gene. 1998 Feb 27;208(2):285-95. doi: 10.1016/s0378-1119(98)00019-5. Gene. 1998. PMID: 9524282

5

Targeted disruption of the mouse lysosomal acid lipase gene: long-term survival with massive cholesteryl ester and triglyceride storage.

Du H, Duanmu M, Witte D, Grabowski GA. Du H, et al. Hum Mol Genet. 1998 Sep;7(9):1347-54. doi: 10.1093/hmg/7.9.1347. Hum Mol Genet. 1998. PMID: 9700186

6

Molecular and enzymatic analyses of lysosomal acid lipase in cholesteryl ester storage disease.

Du H, Sheriff S, Bezerra J, Leonova T, Grabowski GA. Du H, et al. Mol Genet Metab. 1998 Jun;64(2):126-34. doi: 10.1006/mgme.1998.2707. Mol Genet Metab. 1998. PMID: 9705237 Review.

7

Unique cellular events occurring during the initial interaction of macrophages with matrix-retained or methylated aggregated low density lipoprotein (LDL). Prolonged cell-surface contact during which ldl-cholesteryl ester hydrolysis exceeds ldl protein degradation.

Buton X, Mamdouh Z, Ghosh R, Du H, Kuriakose G, Beatini N, Grabowski GA, Maxfield FR, Tabas I. Buton X, et al. Among authors: du h. J Biol Chem. 1999 Nov 5;274(45):32112-21. doi: 10.1074/jbc.274.45.32112. J Biol Chem. 1999. PMID: 10542246 Free article.

8

Phenotypic correction of lipid storage and growth arrest in wolman disease fibroblasts by gene transfer of lysosomal acid lipase.

Tietge UJ, Sun G, Czarnecki S, Yu Q, Lohse P, Du H, Grabowski GA, Glick JM, Rader DJ. Tietge UJ, et al. Among authors: du h. Hum Gene Ther. 2001 Feb 10;12(3):279-89. doi: 10.1089/10430340150218413. Hum Gene Ther. 2001. PMID: 11177564

9

Lysosomal acid lipase-deficient mice: depletion of white and brown fat, severe hepatosplenomegaly, and shortened life span.

Du H, Heur M, Duanmu M, Grabowski GA, Hui DY, Witte DP, Mishra J. Du H, et al. J Lipid Res. 2001 Apr;42(4):489-500. J Lipid Res. 2001. PMID: 11290820 Free article.

10

Enzyme therapy for lysosomal acid lipase deficiency in the mouse.

Du H, Schiavi S, Levine M, Mishra J, Heur M, Grabowski GA. Du H, et al. Hum Mol Genet. 2001 Aug 1;10(16):1639-48. doi: 10.1093/hmg/10.16.1639. Hum Mol Genet. 2001. PMID: 11487567

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