Mounetou E - Search Results

1

A new O6-alkylguanine-DNA alkyltransferase inhibitor associated with a nitrosourea (cystemustine) validates a strategy of melanoma-targeted therapy in murine B16 and human-resistant M4Beu melanoma xenograft models.

Rapp M, Maurizis JC, Papon J, Labarre P, Wu TD, Croisy A, Guerquin-Kern JL, Madelmont JC, Mounetou E. Rapp M, et al. Among authors: mounetou e. J Pharmacol Exp Ther. 2008 Jul;326(1):171-7. doi: 10.1124/jpet.108.137737. Epub 2008 Apr 14. J Pharmacol Exp Ther. 2008. PMID: 18411412

2

Disposition and metabolism of O6-alkylguanine-DNA alkyltransferase inhibitor in nude mice bearing human melanoma.

Cussac C, Mounetou E, Rapp M, Madelmont JC, Maurizis JC, Labarre P, Chollet P, Chabard JL, Godeneche D, Baudry JP, et al. Cussac C, et al. Among authors: mounetou e. Drug Metab Dispos. 1994 Jul-Aug;22(4):637-42. Drug Metab Dispos. 1994. PMID: 7956741

3

Enhancement by O6-benzyl-N-acetylguanosine derivatives of chloroethylnitrosourea antitumor action in chloroethylnitrosourea-resistant human malignant melanocytes.

Cussac C, Rapp M, Mounetou E, Madelmont JC, Maurizis JC, Godeneche D, Dupuy JM, Sauzieres J, Baudry JP, Veyre A. Cussac C, et al. Among authors: mounetou e. J Pharmacol Exp Ther. 1994 Dec;271(3):1353-8. J Pharmacol Exp Ther. 1994. PMID: 7996446

4

O6-(alkyl/aralkyl)guanosine and 2'-deoxyguanosine derivatives: synthesis and ability to enhance chloroethylnitrosourea antitumor action.

Mounetou E, Debiton E, Buchdahl C, Gardette D, Gramain JC, Maurizis JC, Veyre A, Madelmont JC. Mounetou E, et al. J Med Chem. 1997 Aug 29;40(18):2902-9. doi: 10.1021/jm960881d. J Med Chem. 1997. PMID: 9288172

5

Enhancement by O6-benzyl-N2-acetylguanosine of N'-[2-chloroethyl]-N-[2-(methylsulphonyl)ethyl]-N'-nitrosourea therapeutic index on nude mice bearing resistant human melanoma.

Debiton E, Cussac-Buchdhal C, Mounetou E, Rapp M, Dupuy JM, Maurizis JC, Veyre A, Madelmont JC. Debiton E, et al. Among authors: mounetou e. Br J Cancer. 1997;76(9):1157-62. doi: 10.1038/bjc.1997.527. Br J Cancer. 1997. PMID: 9365163 Free PMC article.

6

Melanoma-cell toxicity of cystemustine combined with O6-benzyl-N2-acetylguanosine.

Buchdahl C, Rolhion C, Glasser AL, Debiton E, Mounetou E, Madelmont JC, Laval F. Buchdahl C, et al. Among authors: mounetou e. Melanoma Res. 1998 Apr;8(2):123-30. doi: 10.1097/00008390-199804000-00004. Melanoma Res. 1998. PMID: 9610864

7

Antineoplastic potency of arylchloroethylurea derivatives in murine colon carcinoma.

Miot-Noirault E, Legault J, Cachin F, Mounetou E, Degoul F, Gaudreault RC, Moins N, Madelmont JC. Miot-Noirault E, et al. Among authors: mounetou e. Invest New Drugs. 2004 Nov;22(4):369-78. doi: 10.1023/B:DRUG.0000036679.12112.4c. Invest New Drugs. 2004. PMID: 15292707

8

Alkylation of beta-tubulin on Glu 198 by a microtubule disrupter.

Bouchon B, Chambon C, Mounetou E, Papon J, Miot-Noirault E, Gaudreault RC, Madelmont JC, Degoul F. Bouchon B, et al. Among authors: mounetou e. Mol Pharmacol. 2005 Nov;68(5):1415-22. doi: 10.1124/mol.105.015586. Epub 2005 Aug 12. Mol Pharmacol. 2005. PMID: 16099845

9

N-(4-iodophenyl)-N'-(2-chloroethyl)urea as a microtubule disrupter: in vitro and in vivo profiling of antitumoral activity on CT-26 murine colon carcinoma cell line cultured and grafted to mice.

Borel M, Degoul F, Communal Y, Mounetou E, Bouchon B, C-Gaudreault R, Madelmont JC, Miot-Noirault E. Borel M, et al. Among authors: mounetou e. Br J Cancer. 2007 Jun 4;96(11):1684-91. doi: 10.1038/sj.bjc.6603778. Epub 2007 May 8. Br J Cancer. 2007. PMID: 17486131 Free PMC article.

10

N-4-iodophenyl-N'-2-chloroethylurea, a novel potential anticancer agent with colon-specific accumulation: radioiodination and comparative in vivo biodistribution profiles.

Mounetou E, Miot-Noirault E, Gaudreault RC, Madelmont JC. Mounetou E, et al. Invest New Drugs. 2010 Apr;28(2):124-31. doi: 10.1007/s10637-009-9222-z. Epub 2009 Feb 10. Invest New Drugs. 2010. PMID: 19205625

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