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Page 1
The P2X7 receptor as a therapeutic target.
Romagnoli R, Baraldi PG, Cruz-Lopez O, Lopez-Cara C, Preti D, Borea PA, Gessi S. Romagnoli R, et al. Expert Opin Ther Targets. 2008 May;12(5):647-61. doi: 10.1517/14728222.12.5.647. Expert Opin Ther Targets. 2008. PMID: 18410246 Review.
alpha-halogenoacrylic derivatives of antitumor agents.
Romagnoli R, Baraldi PG, Cruz-Lopez O, Lopez-Cara C, Preti D. Romagnoli R, et al. Mini Rev Med Chem. 2009 Jan;9(1):81-94. doi: 10.2174/138955709787001640. Mini Rev Med Chem. 2009. PMID: 19149662 Review.
Synthesis and biological effects of novel 2-amino-3-(4-chlorobenzoyl)-4-substituted thiophenes as allosteric enhancers of the A1 adenosine receptor.
Romagnoli R, Baraldi PG, Carrion MD, Lopez Cara C, Kimatrai Salvador M, Preti D, Aghazadeh Tabrizi M, Moorman AR, Vincenzi F, Borea PA, Varani K. Romagnoli R, et al. Among authors: lopez cara c. Eur J Med Chem. 2013 Sep;67:409-27. doi: 10.1016/j.ejmech.2013.07.002. Epub 2013 Jul 13. Eur J Med Chem. 2013. PMID: 23911855
Synthesis and biological evaluation of a new series of 2-amino-3-aroyl thiophene derivatives as agonist allosteric modulators of the A1 adenosine receptor. A position-dependent effect study.
Romagnoli R, Baraldi PG, Lopez-Cara C, Cruz-Lopez O, Moorman AR, Massink A, IJzerman AP, Vincenzi F, Borea PA, Varani K. Romagnoli R, et al. Among authors: lopez cara c. Eur J Med Chem. 2015 Aug 28;101:185-204. doi: 10.1016/j.ejmech.2015.06.041. Epub 2015 Jun 24. Eur J Med Chem. 2015. PMID: 26141910
Synthesis and biological evaluation of 2- and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization.
Romagnoli R, Baraldi PG, Carrion MD, Lopez Cara C, Preti D, Fruttarolo F, Pavani MG, Tabrizi MA, Tolomeo M, Grimaudo S, Di Cristina A, Balzarini J, Hadfield JA, Brancale A, Hamel E. Romagnoli R, et al. J Med Chem. 2007 May 3;50(9):2273-7. doi: 10.1021/jm070050f. Epub 2007 Apr 10. J Med Chem. 2007. PMID: 17419607
Synthesis and biological evaluation of 2-(3',4',5'-trimethoxybenzoyl)-3-N,N-dimethylamino benzo[b]furan derivatives as inhibitors of tubulin polymerization.
Romagnoli R, Baraldi PG, Sarkar T, Carrion MD, Cruz-Lopez O, Lopez Cara C, Tolomeo M, Grimaudo S, Di Cristina A, Pipitone MR, Balzarini J, Gambari R, Ilaria L, Saletti R, Brancale A, Hamel E. Romagnoli R, et al. Bioorg Med Chem. 2008 Sep 15;16(18):8419-26. doi: 10.1016/j.bmc.2008.08.029. Epub 2008 Aug 17. Bioorg Med Chem. 2008. PMID: 18755591 Free PMC article.
Symmetrical alpha-bromoacryloylamido diaryldienone derivatives as a novel series of antiproliferative agents. Design, synthesis and biological evaluation.
Romagnoli R, Baraldi PG, Cruz-Lopez O, Lopez Cara C, Carrion MD, Balzarini J, Hamel E, Basso G, Bortolozzi R, Viola G. Romagnoli R, et al. Among authors: lopez cara c. Bioorg Med Chem Lett. 2010 May 1;20(9):2733-9. doi: 10.1016/j.bmcl.2010.03.075. Epub 2010 Mar 25. Bioorg Med Chem Lett. 2010. PMID: 20378350 Free PMC article.
Synthesis and antitumor molecular mechanism of agents based on amino 2-(3',4',5'-trimethoxybenzoyl)benzo[b]furan: inhibition of tubulin and induction of apoptosis.
Romagnoli R, Baraldi PG, Lopez-Cara C, Cruz-Lopez O, Carrion MD, Kimatrai Salvador M, Bermejo J, Estévez S, Estévez F, Balzarini J, Brancale A, Ricci A, Chen L, Kim JG, Hamel E. Romagnoli R, et al. Among authors: lopez cara c. ChemMedChem. 2011 Oct 4;6(10):1841-53. doi: 10.1002/cmdc.201100279. Epub 2011 Aug 1. ChemMedChem. 2011. PMID: 21805646 Free PMC article.
One-pot synthesis and biological evaluation of 2-pyrrolidinyl-4-amino-5-(3',4',5'-trimethoxybenzoyl)thiazole: a unique, highly active antimicrotubule agent.
Romagnoli R, Baraldi PG, Lopez Cara C, Kimatrai Salvador M, Bortolozzi R, Basso G, Viola G, Balzarini J, Brancale A, Fu XH, Li J, Zhang SZ, Hamel E. Romagnoli R, et al. Among authors: lopez cara c. Eur J Med Chem. 2011 Dec;46(12):6015-24. doi: 10.1016/j.ejmech.2011.10.013. Epub 2011 Oct 15. Eur J Med Chem. 2011. PMID: 22027100 Free PMC article.
14 results