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Heat- and anesthesia-induced malignant hyperthermia in an RyR1 knock-in mouse.
Chelu MG, Goonasekera SA, Durham WJ, Tang W, Lueck JD, Riehl J, Pessah IN, Zhang P, Bhattacharjee MB, Dirksen RT, Hamilton SL. Chelu MG, et al. Among authors: goonasekera sa. FASEB J. 2006 Feb;20(2):329-30. doi: 10.1096/fj.05-4497fje. Epub 2005 Nov 11. FASEB J. 2006. PMID: 16284304
An Ryr1I4895T mutation abolishes Ca2+ release channel function and delays development in homozygous offspring of a mutant mouse line.
Zvaritch E, Depreux F, Kraeva N, Loy RE, Goonasekera SA, Boncompagni S, Kraev A, Gramolini AO, Dirksen RT, Franzini-Armstrong C, Seidman CE, Seidman JG, Maclennan DH. Zvaritch E, et al. Among authors: goonasekera sa. Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18537-42. doi: 10.1073/pnas.0709312104. Epub 2007 Nov 14. Proc Natl Acad Sci U S A. 2007. PMID: 18003898 Free PMC article.
Mice with the R176Q cardiac ryanodine receptor mutation exhibit catecholamine-induced ventricular tachycardia and cardiomyopathy.
Kannankeril PJ, Mitchell BM, Goonasekera SA, Chelu MG, Zhang W, Sood S, Kearney DL, Danila CI, De Biasi M, Wehrens XH, Pautler RG, Roden DM, Taffet GE, Dirksen RT, Anderson ME, Hamilton SL. Kannankeril PJ, et al. Among authors: goonasekera sa. Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):12179-84. doi: 10.1073/pnas.0600268103. Epub 2006 Jul 27. Proc Natl Acad Sci U S A. 2006. PMID: 16873551 Free PMC article.
22 results