Binz HK - Search Results

1

Structure of wild-type Plk-1 kinase domain in complex with a selective DARPin.

Bandeiras TM, Hillig RC, Matias PM, Eberspaecher U, Fanghänel J, Thomaz M, Miranda S, Crusius K, Pütter V, Amstutz P, Gulotti-Georgieva M, Binz HK, Holz C, Schmitz AA, Lang C, Donner P, Egner U, Carrondo MA, Müller-Tiemann B. Bandeiras TM, et al. Among authors: binz hk. Acta Crystallogr D Biol Crystallogr. 2008 Apr;64(Pt 4):339-53. doi: 10.1107/S0907444907068217. Epub 2008 Mar 19. Acta Crystallogr D Biol Crystallogr. 2008. PMID: 18391401

2

DARPins: a new generation of protein therapeutics.

Stumpp MT, Binz HK, Amstutz P. Stumpp MT, et al. Among authors: binz hk. Drug Discov Today. 2008 Aug;13(15-16):695-701. doi: 10.1016/j.drudis.2008.04.013. Epub 2008 Jul 11. Drug Discov Today. 2008. PMID: 18621567 Review.

3

Engineering novel binding proteins from nonimmunoglobulin domains.

Binz HK, Amstutz P, Plückthun A. Binz HK, et al. Nat Biotechnol. 2005 Oct;23(10):1257-68. doi: 10.1038/nbt1127. Nat Biotechnol. 2005. PMID: 16211069 Review.

4

Inhibition of caspase-2 by a designed ankyrin repeat protein: specificity, structure, and inhibition mechanism.

Schweizer A, Roschitzki-Voser H, Amstutz P, Briand C, Gulotti-Georgieva M, Prenosil E, Binz HK, Capitani G, Baici A, Plückthun A, Grütter MG. Schweizer A, et al. Among authors: binz hk. Structure. 2007 May;15(5):625-36. doi: 10.1016/j.str.2007.03.014. Structure. 2007. PMID: 17502107 Free article.

5

Rapid selection of specific MAP kinase-binders from designed ankyrin repeat protein libraries.

Amstutz P, Koch H, Binz HK, Deuber SA, Plückthun A. Amstutz P, et al. Among authors: binz hk. Protein Eng Des Sel. 2006 May;19(5):219-29. doi: 10.1093/protein/gzl004. Epub 2006 Mar 21. Protein Eng Des Sel. 2006. PMID: 16551653 Free article.

6

Half-life extension using serum albumin-binding DARPin® domains.

Steiner D, Merz FW, Sonderegger I, Gulotti-Georgieva M, Villemagne D, Phillips DJ, Forrer P, Stumpp MT, Zitt C, Binz HK. Steiner D, et al. Among authors: binz hk. Protein Eng Des Sel. 2017 Sep 1;30(9):583-591. doi: 10.1093/protein/gzx022. Protein Eng Des Sel. 2017. PMID: 29088432

7

Intracellular kinase inhibitors selected from combinatorial libraries of designed ankyrin repeat proteins.

Amstutz P, Binz HK, Parizek P, Stumpp MT, Kohl A, Grütter MG, Forrer P, Plückthun A. Amstutz P, et al. Among authors: binz hk. J Biol Chem. 2005 Jul 1;280(26):24715-22. doi: 10.1074/jbc.M501746200. Epub 2005 Apr 25. J Biol Chem. 2005. PMID: 15851475 Free article.

8

High-affinity binders selected from designed ankyrin repeat protein libraries.

Binz HK, Amstutz P, Kohl A, Stumpp MT, Briand C, Forrer P, Grütter MG, Plückthun A. Binz HK, et al. Nat Biotechnol. 2004 May;22(5):575-82. doi: 10.1038/nbt962. Epub 2004 Apr 18. Nat Biotechnol. 2004. PMID: 15097997

9

Designing repeat proteins: well-expressed, soluble and stable proteins from combinatorial libraries of consensus ankyrin repeat proteins.

Binz HK, Stumpp MT, Forrer P, Amstutz P, Plückthun A. Binz HK, et al. J Mol Biol. 2003 Sep 12;332(2):489-503. doi: 10.1016/s0022-2836(03)00896-9. J Mol Biol. 2003. PMID: 12948497

10

Allosteric inhibition of aminoglycoside phosphotransferase by a designed ankyrin repeat protein.

Kohl A, Amstutz P, Parizek P, Binz HK, Briand C, Capitani G, Forrer P, Plückthun A, Grütter MG. Kohl A, et al. Among authors: binz hk. Structure. 2005 Aug;13(8):1131-41. doi: 10.1016/j.str.2005.04.020. Structure. 2005. PMID: 16084385 Free article.

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