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The NLR gene family: a standard nomenclature.
Ting JP, Lovering RC, Alnemri ES, Bertin J, Boss JM, Davis BK, Flavell RA, Girardin SE, Godzik A, Harton JA, Hoffman HM, Hugot JP, Inohara N, Mackenzie A, Maltais LJ, Nunez G, Ogura Y, Otten LA, Philpott D, Reed JC, Reith W, Schreiber S, Steimle V, Ward PA. Ting JP, et al. Among authors: hoffman hm. Immunity. 2008 Mar;28(3):285-7. doi: 10.1016/j.immuni.2008.02.005. Immunity. 2008. PMID: 18341998 Free PMC article.
MDP-induced interleukin-1beta processing requires Nod2 and CIAS1/NALP3.
Pan Q, Mathison J, Fearns C, Kravchenko VV, Da Silva Correia J, Hoffman HM, Kobayashi KS, Bertin J, Grant EP, Coyle AJ, Sutterwala FS, Ogura Y, Flavell RA, Ulevitch RJ. Pan Q, et al. Among authors: hoffman hm. J Leukoc Biol. 2007 Jul;82(1):177-83. doi: 10.1189/jlb.1006627. Epub 2007 Apr 2. J Leukoc Biol. 2007. PMID: 17403772
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity.
Henao-Mejia J, Elinav E, Jin C, Hao L, Mehal WZ, Strowig T, Thaiss CA, Kau AL, Eisenbarth SC, Jurczak MJ, Camporez JP, Shulman GI, Gordon JI, Hoffman HM, Flavell RA. Henao-Mejia J, et al. Among authors: hoffman hm. Nature. 2012 Feb 1;482(7384):179-85. doi: 10.1038/nature10809. Nature. 2012. PMID: 22297845 Free PMC article.
NLRP3/cryopyrin is necessary for interleukin-1beta (IL-1beta) release in response to hyaluronan, an endogenous trigger of inflammation in response to injury.
Yamasaki K, Muto J, Taylor KR, Cogen AL, Audish D, Bertin J, Grant EP, Coyle AJ, Misaghi A, Hoffman HM, Gallo RL. Yamasaki K, et al. Among authors: hoffman hm. J Biol Chem. 2009 May 8;284(19):12762-71. doi: 10.1074/jbc.M806084200. Epub 2009 Mar 3. J Biol Chem. 2009. PMID: 19258328 Free PMC article.
Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity.
Brydges SD, Mueller JL, McGeough MD, Pena CA, Misaghi A, Gandhi C, Putnam CD, Boyle DL, Firestein GS, Horner AA, Soroosh P, Watford WT, O'Shea JJ, Kastner DL, Hoffman HM. Brydges SD, et al. Among authors: hoffman hm. Immunity. 2009 Jun 19;30(6):875-87. doi: 10.1016/j.immuni.2009.05.005. Epub 2009 Jun 4. Immunity. 2009. PMID: 19501000 Free PMC article.
NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria.
Zhong Z, Umemura A, Sanchez-Lopez E, Liang S, Shalapour S, Wong J, He F, Boassa D, Perkins G, Ali SR, McGeough MD, Ellisman MH, Seki E, Gustafsson AB, Hoffman HM, Diaz-Meco MT, Moscat J, Karin M. Zhong Z, et al. Among authors: hoffman hm. Cell. 2016 Feb 25;164(5):896-910. doi: 10.1016/j.cell.2015.12.057. Cell. 2016. PMID: 26919428 Free PMC article.
179 results