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PPARdelta regulates multiple proinflammatory pathways to suppress atherosclerosis.
Barish GD, Atkins AR, Downes M, Olson P, Chong LW, Nelson M, Zou Y, Hwang H, Kang H, Curtiss L, Evans RM, Lee CH. Barish GD, et al. Among authors: nelson m. Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4271-6. doi: 10.1073/pnas.0711875105. Epub 2008 Mar 12. Proc Natl Acad Sci U S A. 2008. PMID: 18337509 Free PMC article.
SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis.
Nofsinger RR, Li P, Hong SH, Jonker JW, Barish GD, Ying H, Cheng SY, Leblanc M, Xu W, Pei L, Kang YJ, Nelson M, Downes M, Yu RT, Olefsky JM, Lee CH, Evans RM. Nofsinger RR, et al. Among authors: nelson m. Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):20021-6. doi: 10.1073/pnas.0811012105. Epub 2008 Dec 9. Proc Natl Acad Sci U S A. 2008. PMID: 19066220 Free PMC article.
PPARgamma activation in adipocytes is sufficient for systemic insulin sensitization.
Sugii S, Olson P, Sears DD, Saberi M, Atkins AR, Barish GD, Hong SH, Castro GL, Yin YQ, Nelson MC, Hsiao G, Greaves DR, Downes M, Yu RT, Olefsky JM, Evans RM. Sugii S, et al. Among authors: nelson mc. Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22504-9. doi: 10.1073/pnas.0912487106. Epub 2009 Dec 16. Proc Natl Acad Sci U S A. 2009. PMID: 20018750 Free PMC article.
Regulation of muscle fiber type and running endurance by PPARdelta.
Wang YX, Zhang CL, Yu RT, Cho HK, Nelson MC, Bayuga-Ocampo CR, Ham J, Kang H, Evans RM. Wang YX, et al. Among authors: nelson mc. PLoS Biol. 2004 Oct;2(10):e294. doi: 10.1371/journal.pbio.0020294. Epub 2004 Aug 24. PLoS Biol. 2004. PMID: 15328533 Free PMC article.
AMPK and PPARdelta agonists are exercise mimetics.
Narkar VA, Downes M, Yu RT, Embler E, Wang YX, Banayo E, Mihaylova MM, Nelson MC, Zou Y, Juguilon H, Kang H, Shaw RJ, Evans RM. Narkar VA, et al. Among authors: nelson mc. Cell. 2008 Aug 8;134(3):405-15. doi: 10.1016/j.cell.2008.06.051. Epub 2008 Jul 31. Cell. 2008. PMID: 18674809 Free PMC article.
PPAR gamma signaling exacerbates mammary gland tumor development.
Saez E, Rosenfeld J, Livolsi A, Olson P, Lombardo E, Nelson M, Banayo E, Cardiff RD, Izpisua-Belmonte JC, Evans RM. Saez E, et al. Among authors: nelson m. Genes Dev. 2004 Mar 1;18(5):528-40. doi: 10.1101/gad.1167804. Genes Dev. 2004. PMID: 15037548 Free PMC article.
5,410 results