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Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease.
Nuber S, Petrasch-Parwez E, Winner B, Winkler J, von Hörsten S, Schmidt T, Boy J, Kuhn M, Nguyen HP, Teismann P, Schulz JB, Neumann M, Pichler BJ, Reischl G, Holzmann C, Schmitt I, Bornemann A, Kuhn W, Zimmermann F, Servadio A, Riess O. Nuber S, et al. Among authors: nguyen hp. J Neurosci. 2008 Mar 5;28(10):2471-84. doi: 10.1523/JNEUROSCI.3040-07.2008. J Neurosci. 2008. PMID: 18322092 Free PMC article.
Olfactory neuron-specific expression of A30P α-synuclein exacerbates dopamine deficiency and hyperactivity in a novel conditional model of early Parkinson's disease stages.
Nuber S, Petrasch-Parwez E, Arias-Carrión O, Koch L, Kohl Z, Schneider J, Calaminus C, Dermietzel R, Samarina A, Boy J, Nguyen HP, Teismann P, Velavan TP, Kahle PJ, von Hörsten S, Fendt M, Krüger R, Riess O. Nuber S, et al. Among authors: nguyen hp. Neurobiol Dis. 2011 Nov;44(2):192-204. doi: 10.1016/j.nbd.2011.06.017. Epub 2011 Jul 5. Neurobiol Dis. 2011. PMID: 21767644
Olesoxime suppresses calpain activation and mutant huntingtin fragmentation in the BACHD rat.
Clemens LE, Weber JJ, Wlodkowski TT, Yu-Taeger L, Michaud M, Calaminus C, Eckert SH, Gaca J, Weiss A, Magg JC, Jansson EK, Eckert GP, Pichler BJ, Bordet T, Pruss RM, Riess O, Nguyen HP. Clemens LE, et al. Among authors: nguyen hp. Brain. 2015 Dec;138(Pt 12):3632-53. doi: 10.1093/brain/awv290. Epub 2015 Oct 21. Brain. 2015. PMID: 26490331
Overexpression of human wildtype torsinA and human DeltaGAG torsinA in a transgenic mouse model causes phenotypic abnormalities.
Grundmann K, Reischmann B, Vanhoutte G, Hübener J, Teismann P, Hauser TK, Bonin M, Wilbertz J, Horn S, Nguyen HP, Kuhn M, Chanarat S, Wolburg H, Van der Linden A, Riess O. Grundmann K, et al. Among authors: nguyen hp. Neurobiol Dis. 2007 Aug;27(2):190-206. doi: 10.1016/j.nbd.2007.04.015. Epub 2007 May 18. Neurobiol Dis. 2007. PMID: 17601741
Structural and molecular myelination deficits occur prior to neuronal loss in the YAC128 and BACHD models of Huntington disease.
Teo RT, Hong X, Yu-Taeger L, Huang Y, Tan LJ, Xie Y, To XV, Guo L, Rajendran R, Novati A, Calaminus C, Riess O, Hayden MR, Nguyen HP, Chuang KH, Pouladi MA. Teo RT, et al. Among authors: nguyen hp. Hum Mol Genet. 2016 Jul 1;25(13):2621-2632. doi: 10.1093/hmg/ddw122. Epub 2016 Apr 28. Hum Mol Genet. 2016. PMID: 27126634 Free PMC article.
469 results