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Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease.
Nuber S, Petrasch-Parwez E, Winner B, Winkler J, von Hörsten S, Schmidt T, Boy J, Kuhn M, Nguyen HP, Teismann P, Schulz JB, Neumann M, Pichler BJ, Reischl G, Holzmann C, Schmitt I, Bornemann A, Kuhn W, Zimmermann F, Servadio A, Riess O. Nuber S, et al. Among authors: bornemann a. J Neurosci. 2008 Mar 5;28(10):2471-84. doi: 10.1523/JNEUROSCI.3040-07.2008. J Neurosci. 2008. PMID: 18322092 Free PMC article.
Transgenic overexpression of the alpha-synuclein interacting protein synphilin-1 leads to behavioral and neuropathological alterations in mice.
Nuber S, Franck T, Wolburg H, Schumann U, Casadei N, Fischer K, Calaminus C, Pichler BJ, Chanarat S, Teismann P, Schulz JB, Luft AR, Tomiuk J, Wilbertz J, Bornemann A, Krüger R, Riess O. Nuber S, et al. Among authors: bornemann a. Neurogenetics. 2010 Feb;11(1):107-20. doi: 10.1007/s10048-009-0212-2. Neurogenetics. 2010. PMID: 19760259
First appraisal of brain pathology owing to A30P mutant alpha-synuclein.
Seidel K, Schöls L, Nuber S, Petrasch-Parwez E, Gierga K, Wszolek Z, Dickson D, Gai WP, Bornemann A, Riess O, Rami A, Den Dunnen WF, Deller T, Rüb U, Krüger R. Seidel K, et al. Among authors: bornemann a. Ann Neurol. 2010 May;67(5):684-9. doi: 10.1002/ana.21966. Ann Neurol. 2010. PMID: 20437567
Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease.
Strauss KM, Martins LM, Plun-Favreau H, Marx FP, Kautzmann S, Berg D, Gasser T, Wszolek Z, Müller T, Bornemann A, Wolburg H, Downward J, Riess O, Schulz JB, Krüger R. Strauss KM, et al. Among authors: bornemann a. Hum Mol Genet. 2005 Aug 1;14(15):2099-111. doi: 10.1093/hmg/ddi215. Epub 2005 Jun 16. Hum Mol Genet. 2005. PMID: 15961413
Specification of 14-3-3 proteins in Lewy bodies.
Berg D, Riess O, Bornemann A. Berg D, et al. Among authors: bornemann a. Ann Neurol. 2003 Jul;54(1):135. doi: 10.1002/ana.10621. Ann Neurol. 2003. PMID: 12838532 No abstract available.
Ubiquitylation of synphilin-1 and alpha-synuclein by SIAH and its presence in cellular inclusions and Lewy bodies imply a role in Parkinson's disease.
Liani E, Eyal A, Avraham E, Shemer R, Szargel R, Berg D, Bornemann A, Riess O, Ross CA, Rott R, Engelender S. Liani E, et al. Among authors: bornemann a. Proc Natl Acad Sci U S A. 2004 Apr 13;101(15):5500-5. doi: 10.1073/pnas.0401081101. Epub 2004 Apr 2. Proc Natl Acad Sci U S A. 2004. PMID: 15064394 Free PMC article.
166 results