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192 results

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Page 1
Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial.
Davis SM, Donnan GA, Parsons MW, Levi C, Butcher KS, Peeters A, Barber PA, Bladin C, De Silva DA, Byrnes G, Chalk JB, Fink JN, Kimber TE, Schultz D, Hand PJ, Frayne J, Hankey G, Muir K, Gerraty R, Tress BM, Desmond PM; EPITHET investigators. Davis SM, et al. Among authors: de silva da. Lancet Neurol. 2008 Apr;7(4):299-309. doi: 10.1016/S1474-4422(08)70044-9. Epub 2008 Feb 28. Lancet Neurol. 2008. PMID: 18296121 Clinical Trial.
Clinical-diffusion mismatch and benefit from thrombolysis 3 to 6 hours after acute stroke.
Ebinger M, Iwanaga T, Prosser JF, De Silva DA, Christensen S, Collins M, Parsons MW, Levi CR, Bladin CF, Barber PA, Donnan GA, Davis SM; EPITHET Investigators. Ebinger M, et al. Among authors: de silva da. Stroke. 2009 Jul;40(7):2572-4. doi: 10.1161/STROKEAHA.109.548073. Epub 2009 Apr 30. Stroke. 2009. PMID: 19407226 Clinical Trial.
Assessing reperfusion and recanalization as markers of clinical outcomes after intravenous thrombolysis in the echoplanar imaging thrombolytic evaluation trial (EPITHET).
De Silva DA, Fink JN, Christensen S, Ebinger M, Bladin C, Levi CR, Parsons M, Butcher K, Barber PA, Donnan GA, Davis SM; Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET) Investigators. De Silva DA, et al. Stroke. 2009 Aug;40(8):2872-4. doi: 10.1161/STROKEAHA.108.543595. Epub 2009 May 28. Stroke. 2009. PMID: 19478228 Clinical Trial.
Regional very low cerebral blood volume predicts hemorrhagic transformation better than diffusion-weighted imaging volume and thresholded apparent diffusion coefficient in acute ischemic stroke.
Campbell BC, Christensen S, Butcher KS, Gordon I, Parsons MW, Desmond PM, Barber PA, Levi CR, Bladin CF, De Silva DA, Donnan GA, Davis SM; EPITHET Investigators. Campbell BC, et al. Among authors: de silva da. Stroke. 2010 Jan;41(1):82-8. doi: 10.1161/STROKEAHA.109.562116. Epub 2009 Dec 3. Stroke. 2010. PMID: 19959537 Clinical Trial.
The benefits of intravenous thrombolysis relate to the site of baseline arterial occlusion in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET).
De Silva DA, Brekenfeld C, Ebinger M, Christensen S, Barber PA, Butcher KS, Levi CR, Parsons MW, Bladin CF, Donnan GA, Davis SM; Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET) Investigators. De Silva DA, et al. Stroke. 2010 Feb;41(2):295-9. doi: 10.1161/STROKEAHA.109.562827. Epub 2010 Jan 7. Stroke. 2010. PMID: 20056931 Clinical Trial.
Pathophysiological determinants of worse stroke outcome in atrial fibrillation.
Tu HT, Campbell BC, Christensen S, Collins M, De Silva DA, Butcher KS, Parsons MW, Desmond PM, Barber PA, Levi CR, Bladin CF, Donnan GA, Davis SM; Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET) Investigators. Tu HT, et al. Among authors: de silva da. Cerebrovasc Dis. 2010;30(4):389-95. doi: 10.1159/000316886. Epub 2010 Aug 5. Cerebrovasc Dis. 2010. PMID: 20693794 Clinical Trial.
EPITHET: Positive Result After Reanalysis Using Baseline Diffusion-Weighted Imaging/Perfusion-Weighted Imaging Co-Registration.
Nagakane Y, Christensen S, Brekenfeld C, Ma H, Churilov L, Parsons MW, Levi CR, Butcher KS, Peeters A, Barber PA, Bladin CF, De Silva DA, Fink J, Kimber TE, Schultz DW, Muir KW, Tress BM, Desmond PM, Davis SM, Donnan GA; EPITHET Investigators. Nagakane Y, et al. Among authors: de silva da. Stroke. 2011 Jan;42(1):59-64. doi: 10.1161/STROKEAHA.110.580464. Epub 2010 Dec 2. Stroke. 2011. PMID: 21127303 Clinical Trial.
The infarct core is well represented by the acute diffusion lesion: sustained reversal is infrequent.
Campbell BC, Purushotham A, Christensen S, Desmond PM, Nagakane Y, Parsons MW, Lansberg MG, Mlynash M, Straka M, De Silva DA, Olivot JM, Bammer R, Albers GW, Donnan GA, Davis SM; EPITHET–DEFUSE Investigators. Campbell BC, et al. Among authors: de silva da. J Cereb Blood Flow Metab. 2012 Jan;32(1):50-6. doi: 10.1038/jcbfm.2011.102. Epub 2011 Jul 20. J Cereb Blood Flow Metab. 2012. PMID: 21772309 Free PMC article. Clinical Trial.
Fluid-attenuated inversion recovery hyperintensity in acute ischemic stroke may not predict hemorrhagic transformation.
Campbell BC, Costello C, Christensen S, Ebinger M, Parsons MW, Desmond PM, Barber PA, Butcher KS, Levi CR, De Silva DA, Lansberg MG, Mlynash M, Olivot JM, Straka M, Bammer R, Albers GW, Donnan GA, Davis SM; EPITHET-DEFUSE Investigators. Campbell BC, et al. Among authors: de silva da. Cerebrovasc Dis. 2011;32(4):401-5. doi: 10.1159/000331467. Epub 2011 Oct 8. Cerebrovasc Dis. 2011. PMID: 21986096 Free PMC article.
Greater effect of stroke thrombolysis in the presence of arterial obstruction.
De Silva DA, Churilov L, Olivot JM, Christensen S, Lansberg MG, Mlynash M, Campbell BC, Desmond P, Straka M, Bammer R, Albers GW, Davis SM, Donnan GA; EPITHET-DEFUSE Investigators. De Silva DA, et al. Ann Neurol. 2011 Oct;70(4):601-5. doi: 10.1002/ana.22444. Ann Neurol. 2011. PMID: 22028220 Free PMC article. Clinical Trial.
192 results