Specht S - Search Results

1

Pleural cellular reaction to the filarial infection Litomosoides sigmodontis is determined by the moulting process, the worm alteration, and the host strain.

Attout T, Martin C, Babayan SA, Kozek WJ, Bazzocchi C, Oudet F, Gallagher IJ, Specht S, Bain O. Attout T, et al. Among authors: specht s. Parasitol Int. 2008 Jun;57(2):201-11. doi: 10.1016/j.parint.2008.01.001. Epub 2008 Feb 4. Parasitol Int. 2008. PMID: 18295534

2

Increased early local immune responses and altered worm development in high-dose infections of mice susceptible to the filaria Litomosoides sigmodontis.

Babayan S, Attout T, Specht S, Hoerauf A, Snounou G, Rénia L, Korenaga M, Bain O, Martin C. Babayan S, et al. Among authors: specht s. Med Microbiol Immunol. 2005 May;194(3):151-62. doi: 10.1007/s00430-004-0226-1. Epub 2004 Aug 26. Med Microbiol Immunol. 2005. PMID: 15338299

3

Lymphatic vascularisation and involvement of Lyve-1+ macrophages in the human onchocerca nodule.

Attout T, Hoerauf A, Dénécé G, Debrah AY, Marfo-Debrekyei Y, Boussinesq M, Wanji S, Martinez V, Mand S, Adjei O, Bain O, Specht S, Martin C. Attout T, et al. Among authors: specht s. PLoS One. 2009 Dec 9;4(12):e8234. doi: 10.1371/journal.pone.0008234. PLoS One. 2009. PMID: 20011036 Free PMC article.

4

Immunization with L. sigmodontis microfilariae reduces peripheral microfilaraemia after challenge infection by inhibition of filarial embryogenesis.

Ziewer S, Hübner MP, Dubben B, Hoffmann WH, Bain O, Martin C, Hoerauf A, Specht S. Ziewer S, et al. Among authors: specht s. PLoS Negl Trop Dis. 2012;6(3):e1558. doi: 10.1371/journal.pntd.0001558. Epub 2012 Mar 6. PLoS Negl Trop Dis. 2012. PMID: 22413031 Free PMC article.

5

Migratory phase of Litomosoides sigmodontis filarial infective larvae is associated with pathology and transient increase of S100A9 expressing neutrophils in the lung.

Karadjian G, Fercoq F, Pionnier N, Vallarino-Lhermitte N, Lefoulon E, Nieguitsila A, Specht S, Carlin LM, Martin C. Karadjian G, et al. Among authors: specht s. PLoS Negl Trop Dis. 2017 May 9;11(5):e0005596. doi: 10.1371/journal.pntd.0005596. eCollection 2017 May. PLoS Negl Trop Dis. 2017. PMID: 28486498 Free PMC article.

6

Oxfendazole mediates macrofilaricidal efficacy against the filarial nematode Litomosoides sigmodontis in vivo and inhibits Onchocerca spec. motility in vitro.

Hübner MP, Martin C, Specht S, Koschel M, Dubben B, Frohberger SJ, Ehrens A, Fendler M, Struever D, Mitre E, Vallarino-Lhermitte N, Gokool S, Lustigman S, Schneider M, Townson S, Hoerauf A, Scandale I. Hübner MP, et al. Among authors: specht s. PLoS Negl Trop Dis. 2020 Jul 6;14(7):e0008427. doi: 10.1371/journal.pntd.0008427. eCollection 2020 Jul. PLoS Negl Trop Dis. 2020. PMID: 32628671 Free PMC article.

7

CCL17 controls mast cells for the defense against filarial larval entry.

Specht S, Frank JK, Alferink J, Dubben B, Layland LE, Denece G, Bain O, Förster I, Kirschning CJ, Martin C, Hoerauf A. Specht S, et al. J Immunol. 2011 Apr 15;186(8):4845-52. doi: 10.4049/jimmunol.1000612. Epub 2011 Mar 11. J Immunol. 2011. PMID: 21398605

8

Murine filariasis: interleukin 4 and interleukin 5 lead to containment of different worm developmental stages.

Volkmann L, Bain O, Saeftel M, Specht S, Fischer K, Brombacher F, Matthaei KI, Hoerauf A. Volkmann L, et al. Among authors: specht s. Med Microbiol Immunol. 2003 Feb;192(1):23-31. doi: 10.1007/s00430-002-0155-9. Epub 2002 Dec 10. Med Microbiol Immunol. 2003. PMID: 12592560

9

Combinations of registered drugs reduce treatment times required to deplete Wolbachia in the Litomosoides sigmodontis mouse model.

Specht S, Pfarr KM, Arriens S, Hübner MP, Klarmann-Schulz U, Koschel M, Sternberg S, Martin C, Ford L, Taylor MJ, Hoerauf A. Specht S, et al. PLoS Negl Trop Dis. 2018 Jan 4;12(1):e0006116. doi: 10.1371/journal.pntd.0006116. eCollection 2018 Jan. PLoS Negl Trop Dis. 2018. PMID: 29300732 Free PMC article.

10

Filarial nematode phenotypic screening cascade to identify compounds with anti-parasitic activity for drug discovery optimization.

Hawryluk N, Zhiru L, Carlow C, Gokool S, Townson S, Kreiss T, Chojnowski A, Prorok M, Siekierka J, Ehrens A, Koschel M, Lhermitte-Vallarino N, Martin C, Hoerauf A, Hernandez G, Canan S, Khetani V, Zeldis J, Specht S, Hübner MP, Scandale I. Hawryluk N, et al. Among authors: specht s. Int J Parasitol Drugs Drug Resist. 2022 Aug;19:89-97. doi: 10.1016/j.ijpddr.2022.06.002. Epub 2022 Jun 23. Int J Parasitol Drugs Drug Resist. 2022. PMID: 35834918 Free PMC article.

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