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The cephalostatin way of apoptosis.
J Nat Prod. 2008 Mar;71(3):482-6. doi: 10.1021/np070534e. Epub 2008 Feb 8.
J Nat Prod. 2008.
PMID: 18257532
Review.
Role of Smac in cephalostatin-induced cell death.
Rudy A, López-Antón N, Barth N, Pettit GR, Dirsch VM, Schulze-Osthoff K, Rehm M, Prehn JH, Vogler M, Fulda S, Vollmar AM.
Rudy A, et al. Among authors: lopez anton n.
Cell Death Differ. 2008 Dec;15(12):1930-40. doi: 10.1038/cdd.2008.125. Epub 2008 Sep 19.
Cell Death Differ. 2008.
PMID: 18806754
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Cephalostatin 1 inactivates Bcl-2 by hyperphosphorylation independent of M-phase arrest and DNA damage.
Müller IM, Dirsch VM, Rudy A, López-Antón N, Pettit GR, Vollmar AM.
Müller IM, et al. Among authors: lopez anton n.
Mol Pharmacol. 2005 May;67(5):1684-9. doi: 10.1124/mol.104.004234. Epub 2005 Feb 9.
Mol Pharmacol. 2005.
PMID: 15703383
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The marine product cephalostatin 1 activates an endoplasmic reticulum stress-specific and apoptosome-independent apoptotic signaling pathway.
López-Antón N, Rudy A, Barth N, Schmitz ML, Pettit GR, Schulze-Osthoff K, Dirsch VM, Vollmar AM.
López-Antón N, et al.
J Biol Chem. 2006 Nov 3;281(44):33078-86. doi: 10.1074/jbc.M607904200. Epub 2006 Aug 31.
J Biol Chem. 2006.
PMID: 16945918
Free article.
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Sesquiterpene lactones induce distinct forms of cell death that modulate human monocyte-derived macrophage responses.
López-Antón N, Hermann C, Murillo R, Merfort I, Wanner G, Vollmar AM, Dirsch VM.
López-Antón N, et al.
Apoptosis. 2007 Jan;12(1):141-53. doi: 10.1007/s10495-006-0331-2.
Apoptosis. 2007.
PMID: 17080325
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Helenalin bypasses Bcl-2-mediated cell death resistance by inhibiting NF-κB and promoting reactive oxygen species generation.
Hoffmann R, von Schwarzenberg K, López-Antón N, Rudy A, Wanner G, Dirsch VM, Vollmar AM.
Hoffmann R, et al. Among authors: lopez anton n.
Biochem Pharmacol. 2011 Sep 1;82(5):453-63. doi: 10.1016/j.bcp.2011.05.029. Epub 2011 Jun 2.
Biochem Pharmacol. 2011.
PMID: 21669190
Free article.
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Development of a novel mammalian display system for selection of antibodies against membrane proteins.
Robertson N, Lopez-Anton N, Gurjar SA, Khalique H, Khalaf Z, Clerkin S, Leydon VR, Parker-Manuel R, Raeside A, Payne T, Jones TD, Seymour L, Cawood R.
Robertson N, et al. Among authors: lopez anton n.
J Biol Chem. 2020 Dec 25;295(52):18436-18448. doi: 10.1074/jbc.RA120.015053. Epub 2020 Oct 30.
J Biol Chem. 2020.
PMID: 33127646
Free PMC article.
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