Minato K - Search Results

1

Biotransformation of 3-amino-5,6,7,8-tetrahydro-2-{4-[4-(quinolin-2-yl)piperazin-1-yl]butyl}quinazolin-4(3H)-one (TZB-30878), a novel 5-hydroxytryptamine (5-HT)1A agonist/5-HT3 antagonist, in human hepatic cytochrome P450 enzymes.

Minato K, Suzuki R, Asagarasu A, Matsui T, Sato M. Minato K, et al. Drug Metab Dispos. 2008 May;36(5):831-40. doi: 10.1124/dmd.107.018168. Epub 2008 Jan 31. Drug Metab Dispos. 2008. PMID: 18238859

2

Discovery of a novel 5-HT(3) antagonist/5-HT(1A) agonist 3-amino-5,6,7,8-tetrahydro-2-{4-[4-(quinolin-2-yl)piperazin-1-yl]butyl}quinazolin-4(3H)-one (TZB-30878) as an orally bioavailable agent for irritable bowel syndrome.

Asagarasu A, Matsui T, Hayashi H, Tamaoki S, Yamauchi Y, Minato K, Sato M. Asagarasu A, et al. Among authors: minato k. J Med Chem. 2010 Nov 11;53(21):7549-63. doi: 10.1021/jm1002292. J Med Chem. 2010. PMID: 20931963

3

Development of analytical method for simultaneous determination of five rodent unique bile acids in rat plasma using ultra-performance liquid chromatography coupled with time-of-flight mass spectrometry.

Minato K, Suzuki M, Nagao H, Suzuki R, Ochiai H. Minato K, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 1;1002:399-410. doi: 10.1016/j.jchromb.2015.08.047. Epub 2015 Sep 3. J Chromatogr B Analyt Technol Biomed Life Sci. 2015. PMID: 26363851

4

Development and Validation of LC-MS/MS Assay for the Quantification of Progesterone in Rat Plasma and its Application to Pharmacokinetic Studies.

Sasaki M, Ochiai H, Takahashi K, Suzuki R, Minato K, Fujikata A. Sasaki M, et al. Among authors: minato k. Drug Res (Stuttg). 2015 Sep;65(9):484-9. doi: 10.1055/s-0034-1389967. Epub 2014 Sep 29. Drug Res (Stuttg). 2015. PMID: 25264857

5

Development of a high-performance liquid chromatography-tandem mass spectrometric method for the determination of Methimazole in human blood matrices.

Ito Y, Sakai H, Nagao H, Suzuki R, Odawara M, Minato K. Ito Y, et al. Among authors: minato k. J Chromatogr B Analyt Technol Biomed Life Sci. 2020 May 1;1144:122083. doi: 10.1016/j.jchromb.2020.122083. Epub 2020 Mar 27. J Chromatogr B Analyt Technol Biomed Life Sci. 2020. PMID: 32251990

6

Analysis of the disposition of a novel p38 MAPK inhibitor, AKP-001, and its metabolites in rats with a simple physiologically based pharmacokinetic model.

Shirota K, Kaneko M, Sasaki M, Minato K, Fujikata A, Ohta S, Hisaka A, Suzuki H. Shirota K, et al. Among authors: minato k. Drug Metab Dispos. 2015 Feb;43(2):217-26. doi: 10.1124/dmd.114.060046. Epub 2014 Nov 24. Drug Metab Dispos. 2015. PMID: 25422274

7

Pharmacokinetics and biliary excretion of osaterone acetate, a new steroidal antiandrogen, in dogs.

Minato K, Koizumi N, Honma S, Tsukamoto K, Iwamura S. Minato K, et al. Drug Metab Dispos. 2002 Feb;30(2):167-72. doi: 10.1124/dmd.30.2.167. Drug Metab Dispos. 2002. PMID: 11792686

8

Characterizations of mouse hepatic microsomal monooxygenase catalyzing 11beta-hydroxylation of osaterone acetate.

Minato K, Koizumi N, Honma S, Iwamura S, Tsukamoto K. Minato K, et al. Biochem Pharmacol. 1999 Jul 15;58(2):335-41. doi: 10.1016/s0006-2952(99)00098-2. Biochem Pharmacol. 1999. PMID: 10423176

9

[Biosynthesis of androgen].

Minato K, Honma S. Minato K, et al. Nihon Rinsho. 2006 Apr;64 Suppl 4:455-64. Nihon Rinsho. 2006. PMID: 16689350 Review. Japanese. No abstract available.

10

Metabolism of osaterone acetate in dogs and humans.

Minato K, Honma S, Shinohara Y, Hashimoto T. Minato K, et al. Steroids. 2005 Aug;70(9):563-72. doi: 10.1016/j.steroids.2005.03.012. Steroids. 2005. PMID: 15923016

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