Lipkind GM - Search Results

1

Mutations in the insulin gene can cause MODY and autoantibody-negative type 1 diabetes.

Molven A, Ringdal M, Nordbø AM, Raeder H, Støy J, Lipkind GM, Steiner DF, Philipson LH, Bergmann I, Aarskog D, Undlien DE, Joner G, Søvik O; Norwegian Childhood Diabetes Study Group; Bell GI, Njølstad PR. Molven A, et al. Among authors: lipkind gm. Diabetes. 2008 Apr;57(4):1131-5. doi: 10.2337/db07-1467. Epub 2008 Jan 11. Diabetes. 2008. PMID: 18192540

2

Insulin gene mutations as a cause of permanent neonatal diabetes.

Støy J, Edghill EL, Flanagan SE, Ye H, Paz VP, Pluzhnikov A, Below JE, Hayes MG, Cox NJ, Lipkind GM, Lipton RB, Greeley SA, Patch AM, Ellard S, Steiner DF, Hattersley AT, Philipson LH, Bell GI; Neonatal Diabetes International Collaborative Group. Støy J, et al. Among authors: lipkind gm. Proc Natl Acad Sci U S A. 2007 Sep 18;104(38):15040-4. doi: 10.1073/pnas.0707291104. Epub 2007 Sep 12. Proc Natl Acad Sci U S A. 2007. PMID: 17855560 Free PMC article.

3

Predicted structural alterations in proinsulin during its interactions with prohormone convertases.

Lipkind G, Steiner DF. Lipkind G, et al. Biochemistry. 1999 Jan 19;38(3):890-6. doi: 10.1021/bi981556q. Biochemistry. 1999. PMID: 9893983

4

Identification of 14 new glucokinase mutations and description of the clinical profile of 42 MODY-2 families.

Velho G, Blanché H, Vaxillaire M, Bellanné-Chantelot C, Pardini VC, Timsit J, Passa P, Deschamps I, Robert JJ, Weber IT, Marotta D, Pilkis SJ, Lipkind GM, Bell GI, Froguel P. Velho G, et al. Among authors: lipkind gm. Diabetologia. 1997 Feb;40(2):217-24. doi: 10.1007/s001250050666. Diabetologia. 1997. PMID: 9049484

5

Congenital insulin resistance associated with a conformational alteration in a conserved beta-sheet in the insulin receptor L1 domain.

Rouard M, Bass J, Grigorescu F, Garrett TP, Ward CW, Lipkind G, Jaffiole C, Steiner DF, Bell GI. Rouard M, et al. J Biol Chem. 1999 Jun 25;274(26):18487-91. doi: 10.1074/jbc.274.26.18487. J Biol Chem. 1999. PMID: 10373457 Free article.

6

Molecular modeling of the substrate specificity of prohormone convertases SPC2 and SPC3.

Lipkind G, Gong Q, Steiner DF. Lipkind G, et al. J Biol Chem. 1995 Jun 2;270(22):13277-84. doi: 10.1074/jbc.270.22.13277. J Biol Chem. 1995. PMID: 7768927 Free article.

7

A model for the structure of the P domains in the subtilisin-like prohormone convertases.

Lipkind GM, Zhou A, Steiner DF. Lipkind GM, et al. Proc Natl Acad Sci U S A. 1998 Jun 23;95(13):7310-5. doi: 10.1073/pnas.95.13.7310. Proc Natl Acad Sci U S A. 1998. PMID: 9636145 Free PMC article.

8

Mutational analysis of predicted interactions between the catalytic and P domains of prohormone convertase 3 (PC3/PC1).

Ueda K, Lipkind GM, Zhou A, Zhu X, Kuznetsov A, Philipson L, Gardner P, Zhang C, Steiner DF. Ueda K, et al. Among authors: lipkind gm. Proc Natl Acad Sci U S A. 2003 May 13;100(10):5622-7. doi: 10.1073/pnas.0631617100. Epub 2003 Apr 29. Proc Natl Acad Sci U S A. 2003. PMID: 12721373 Free PMC article.

9

Regulatory roles of the P domain of the subtilisin-like prohormone convertases.

Zhou A, Martin S, Lipkind G, LaMendola J, Steiner DF. Zhou A, et al. J Biol Chem. 1998 May 1;273(18):11107-14. doi: 10.1074/jbc.273.18.11107. J Biol Chem. 1998. PMID: 9556596 Free article.

10

Significance of prohormone convertase 2, PC2, mediated initial cleavage at the proglucagon interdomain site, Lys70-Arg71, to generate glucagon.

Dey A, Lipkind GM, Rouillé Y, Norrbom C, Stein J, Zhang C, Carroll R, Steiner DF. Dey A, et al. Among authors: lipkind gm. Endocrinology. 2005 Feb;146(2):713-27. doi: 10.1210/en.2004-1118. Epub 2004 Nov 4. Endocrinology. 2005. PMID: 15528303

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