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An expeditious synthesis of tamoxifen, a representative SERM (selective estrogen receptor modulator), via the three-component coupling reaction among aromatic aldehyde, cinnamyltrimethylsilane, and beta-chlorophenetole.
Shiina I, Sano Y, Nakata K, Suzuki M, Yokoyama T, Sasaki A, Orikasa T, Miyamoto T, Ikekita M, Nagahara Y, Hasome Y. Shiina I, et al. Among authors: ikekita m. Bioorg Med Chem. 2007 Dec 15;15(24):7599-617. doi: 10.1016/j.bmc.2007.09.008. Epub 2007 Sep 12. Bioorg Med Chem. 2007. PMID: 17904372
Novel tamoxifen derivative Ridaifen-B induces Bcl-2 independent autophagy without estrogen receptor involvement.
Nagahara Y, Takeyoshi M, Sakemoto S, Shiina I, Nakata K, Fujimori K, Wang Y, Umeda E, Watanabe C, Uetake S, Yamori T, Dan S, Yoshimi Y, Shinomiya T, Ikekita M. Nagahara Y, et al. Among authors: ikekita m. Biochem Biophys Res Commun. 2013 Jun 14;435(4):657-63. doi: 10.1016/j.bbrc.2013.05.040. Epub 2013 May 18. Biochem Biophys Res Commun. 2013. PMID: 23688426
Coenzyme Q2 induced p53-dependent apoptosis.
Esaka Y, Nagahara Y, Hasome Y, Nishio R, Ikekita M. Esaka Y, et al. Among authors: ikekita m. Biochim Biophys Acta. 2005 Jun 20;1724(1-2):49-58. doi: 10.1016/j.bbagen.2005.04.013. Biochim Biophys Acta. 2005. PMID: 15905035
Apoptosis-inducing effect of epolactaene derivatives on BALL-1 cells.
Kuramochi K, Matsui R, Matsubara Y, Nakai J, Sunoki T, Arai S, Nagata S, Nagahara Y, Mizushina Y, Ikekita M, Kobayashi S. Kuramochi K, et al. Among authors: ikekita m. Bioorg Med Chem. 2006 Apr 1;14(7):2151-61. doi: 10.1016/j.bmc.2005.10.057. Epub 2005 Nov 18. Bioorg Med Chem. 2006. PMID: 16298530
92 results