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Bornyl (3,4,5-trihydroxy)-cinnamate--an optimized human neutrophil elastase inhibitor designed by free energy calculations.
Bioorg Med Chem. 2008 Mar 1;16(5):2385-90. doi: 10.1016/j.bmc.2007.11.070. Epub 2007 Nov 29.
Bioorg Med Chem. 2008.
PMID: 18078761
Plant phenolics inhibit neutrophil elastase.
Hrenn A, Steinbrecher T, Labahn A, Schwager J, Schempp CM, Merfort I.
Hrenn A, et al.
Planta Med. 2006 Oct;72(12):1127-31. doi: 10.1055/s-2006-946700.
Planta Med. 2006.
PMID: 17024589
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Natural compounds as inhibitors of human neutrophil elastase.
Siedle B, Hrenn A, Merfort I.
Siedle B, et al. Among authors: hrenn a.
Planta Med. 2007 May;73(5):401-20. doi: 10.1055/s-2007-967183. Epub 2007 Apr 20.
Planta Med. 2007.
PMID: 17447201
Review.
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Sesquiterpene lactones as inhibitors of IL-8 expression in HeLa cells.
Lindenmeyer MT, Hrenn A, Kern C, Castro V, Murillo R, Müller S, Laufer S, Schulte-Mönting J, Siedle B, Merfort I.
Lindenmeyer MT, et al. Among authors: hrenn a.
Bioorg Med Chem. 2006 Apr 15;14(8):2487-97. doi: 10.1016/j.bmc.2005.11.027. Epub 2005 Dec 1.
Bioorg Med Chem. 2006.
PMID: 16326104
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A new assay format for NF-kappaB based on a DNA triple helix and a fluorescence resonance energy transfer.
Altevogt D, Hrenn A, Kern C, Clima L, Bannwarth W, Merfort I.
Altevogt D, et al. Among authors: hrenn a.
Org Biomol Chem. 2009 Oct 7;7(19):3934-9. doi: 10.1039/b906447h. Epub 2009 Jul 17.
Org Biomol Chem. 2009.
PMID: 19763295
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Phytomedicines prepared from Arnica flowers inhibit the transcription factors AP-1 and NF-kappaB and modulate the activity of MMP1 and MMP13 in human and bovine chondrocytes.
Jäger C, Hrenn A, Zwingmann J, Suter A, Merfort I.
Jäger C, et al. Among authors: hrenn a.
Planta Med. 2009 Oct;75(12):1319-25. doi: 10.1055/s-0029-1185668. Epub 2009 May 8.
Planta Med. 2009.
PMID: 19431101
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