Marr R - Search Results

1

Novel strategies for Alzheimer's disease treatment.

Spencer B, Rockenstein E, Crews L, Marr R, Masliah E. Spencer B, et al. Among authors: marr r. Expert Opin Biol Ther. 2007 Dec;7(12):1853-67. doi: 10.1517/14712598.7.12.1853. Expert Opin Biol Ther. 2007. PMID: 18034651 Review.

2

Neprilysin gene transfer reduces human amyloid pathology in transgenic mice.

Marr RA, Rockenstein E, Mukherjee A, Kindy MS, Hersh LB, Gage FH, Verma IM, Masliah E. Marr RA, et al. J Neurosci. 2003 Mar 15;23(6):1992-6. doi: 10.1523/JNEUROSCI.23-06-01992.2003. J Neurosci. 2003. PMID: 12657655 Free PMC article.

3

Neprilysin regulates amyloid Beta peptide levels.

Marr RA, Guan H, Rockenstein E, Kindy M, Gage FH, Verma I, Masliah E, Hersh LB. Marr RA, et al. J Mol Neurosci. 2004;22(1-2):5-11. doi: 10.1385/JMN:22:1-2:5. J Mol Neurosci. 2004. PMID: 14742905

4

An antiaggregation gene therapy strategy for Lewy body disease utilizing beta-synuclein lentivirus in a transgenic model.

Hashimoto M, Rockenstein E, Mante M, Crews L, Bar-On P, Gage FH, Marr R, Masliah E. Hashimoto M, et al. Among authors: marr r. Gene Ther. 2004 Dec;11(23):1713-23. doi: 10.1038/sj.gt.3302349. Gene Ther. 2004. PMID: 15483670

5

Targeting BACE1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model.

Singer O, Marr RA, Rockenstein E, Crews L, Coufal NG, Gage FH, Verma IM, Masliah E. Singer O, et al. Nat Neurosci. 2005 Oct;8(10):1343-9. doi: 10.1038/nn1531. Epub 2005 Aug 28. Nat Neurosci. 2005. PMID: 16136043

6

Long-term neprilysin gene transfer is associated with reduced levels of intracellular Abeta and behavioral improvement in APP transgenic mice.

Spencer B, Marr RA, Rockenstein E, Crews L, Adame A, Potkar R, Patrick C, Gage FH, Verma IM, Masliah E. Spencer B, et al. Among authors: marr ra. BMC Neurosci. 2008 Nov 12;9:109. doi: 10.1186/1471-2202-9-109. BMC Neurosci. 2008. PMID: 19014502 Free PMC article.

7

Neuropeptide Y fragments derived from neprilysin processing are neuroprotective in a transgenic model of Alzheimer's disease.

Rose JB, Crews L, Rockenstein E, Adame A, Mante M, Hersh LB, Gage FH, Spencer B, Potkar R, Marr RA, Masliah E. Rose JB, et al. Among authors: marr ra. J Neurosci. 2009 Jan 28;29(4):1115-25. doi: 10.1523/JNEUROSCI.4220-08.2009. J Neurosci. 2009. PMID: 19176820 Free PMC article.

8

NEP-like endopeptidases and Alzheimer's disease [corrected].

Marr RA, Spencer BJ. Marr RA, et al. Curr Alzheimer Res. 2010 May;7(3):223-9. doi: 10.2174/156720510791050849. Curr Alzheimer Res. 2010. PMID: 20088804 Review.

9

Neprilysin-2 is an important β-amyloid degrading enzyme.

Hafez D, Huang JY, Huynh AM, Valtierra S, Rockenstein E, Bruno AM, Lu B, DesGroseillers L, Masliah E, Marr RA. Hafez D, et al. Am J Pathol. 2011 Jan;178(1):306-12. doi: 10.1016/j.ajpath.2010.11.012. Epub 2010 Dec 23. Am J Pathol. 2011. PMID: 21224067 Free PMC article.

10

Peripheral delivery of a CNS targeted, metalo-protease reduces aβ toxicity in a mouse model of Alzheimer's disease.

Spencer B, Marr RA, Gindi R, Potkar R, Michael S, Adame A, Rockenstein E, Verma IM, Masliah E. Spencer B, et al. Among authors: marr ra. PLoS One. 2011 Jan 31;6(1):e16575. doi: 10.1371/journal.pone.0016575. PLoS One. 2011. PMID: 21304989 Free PMC article.

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