Hicken EJ - Search Results

1

Phase-transfer-catalyzed asymmetric acylimidazole alkylation.

Andrus MB, Christiansen MA, Hicken EJ, Gainer MJ, Bedke DK, Harper KC, Mikkelson SR, Dodson DS, Harris DT. Andrus MB, et al. Among authors: hicken ej. Org Lett. 2007 Nov 8;9(23):4865-8. doi: 10.1021/ol702197r. Epub 2007 Oct 18. Org Lett. 2007. PMID: 17944480

2

Total synthesis of (+)-geldanamycin and (-)-o-quinogeldanamycin with use of asymmetric anti- and syn-glycolate aldol reactions.

Andrus MB, Meredith EL, Simmons BL, Soma Sekhar BB, Hicken EJ. Andrus MB, et al. Among authors: hicken ej. Org Lett. 2002 Oct 3;4(20):3549-52. doi: 10.1021/ol0267432. Org Lett. 2002. PMID: 12323066

3

Selective synthesis of the para-quinone region of geldanamycin.

Andrus MB, Hicken EJ, Meredith EL, Simmons BL, Cannon JF. Andrus MB, et al. Among authors: hicken ej. Org Lett. 2003 Oct 16;5(21):3859-62. doi: 10.1021/ol035400g. Org Lett. 2003. PMID: 14535728

4

Phase-transfer-catalyzed asymmetric glycolate alkylation.

Andrus MB, Hicken EJ, Stephens JC. Andrus MB, et al. Among authors: hicken ej. Org Lett. 2004 Jun 24;6(13):2289-92. doi: 10.1021/ol0491235. Org Lett. 2004. PMID: 15200342

5

Asymmetric phase-transfer catalyzed glycolate alkylation, investigation of the scope, and application to the synthesis of (-)-ragaglitazar.

Andrus MB, Hicken EJ, Stephens JC, Bedke DK. Andrus MB, et al. Among authors: hicken ej. J Org Chem. 2005 Nov 11;70(23):9470-9. doi: 10.1021/jo051568z. J Org Chem. 2005. PMID: 16268622

6

Total synthesis of the hydroxyketone kurasoin A using asymmetric phase-transfer alkylation.

Andrus MB, Hicken EJ, Stephens JC, Bedke DK. Andrus MB, et al. Among authors: hicken ej. J Org Chem. 2006 Oct 27;71(22):8651-4. doi: 10.1021/jo061395t. J Org Chem. 2006. PMID: 17064051

7

Total synthesis of (+)-geldanamycin and (-)-o-quinogeldanamycin: asymmetric glycolate aldol reactions and biological evaluation.

Andrus MB, Meredith EL, Hicken EJ, Simmons BL, Glancey RR, Ma W. Andrus MB, et al. Among authors: hicken ej. J Org Chem. 2003 Oct 17;68(21):8162-9. doi: 10.1021/jo034870l. J Org Chem. 2003. PMID: 14535799

8

Stereoselective synthesis of woody fragrances related to georgyone and arborone.

Hicken EJ, Corey EJ. Hicken EJ, et al. Org Lett. 2008 Mar 20;10(6):1135-8. doi: 10.1021/ol8000359. Epub 2008 Feb 28. Org Lett. 2008. PMID: 18303897

9

Discovery of Potent and Selective Covalent Inhibitors of HER2^WT and HER2^YVMA.

Hicken EJ, Brown K, Dwulet NC, Gaudino JJ, Hansen EP, Hartley DP, Kowalski JP, Laird ER, Lazzara NC, Li B, Mou TC, Mutryn MF, Oko L, Pajk S, Pipal RW, Rosen RZ, Shelp R, Singh A, Wang J, Wise CE, Wong C, Wong JY. Hicken EJ, et al. J Med Chem. 2024 May 31. doi: 10.1021/acs.jmedchem.4c00978. Online ahead of print. J Med Chem. 2024. PMID: 38820338

10

Identification of the Clinical Development Candidate MRTX849, a Covalent KRAS^G12C Inhibitor for the Treatment of Cancer.

Fell JB, Fischer JP, Baer BR, Blake JF, Bouhana K, Briere DM, Brown KD, Burgess LE, Burns AC, Burkard MR, Chiang H, Chicarelli MJ, Cook AW, Gaudino JJ, Hallin J, Hanson L, Hartley DP, Hicken EJ, Hingorani GP, Hinklin RJ, Mejia MJ, Olson P, Otten JN, Rhodes SP, Rodriguez ME, Savechenkov P, Smith DJ, Sudhakar N, Sullivan FX, Tang TP, Vigers GP, Wollenberg L, Christensen JG, Marx MA. Fell JB, et al. Among authors: hicken ej. J Med Chem. 2020 Jul 9;63(13):6679-6693. doi: 10.1021/acs.jmedchem.9b02052. Epub 2020 Apr 6. J Med Chem. 2020. PMID: 32250617 Free article.

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