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Early detection of Alzheimer's disease with PET imaging.
Berti V, Osorio RS, Mosconi L, Li Y, De Santi S, de Leon MJ. Berti V, et al. Among authors: li y. Neurodegener Dis. 2010;7(1-3):131-5. doi: 10.1159/000289222. Epub 2010 Mar 3. Neurodegener Dis. 2010. PMID: 20197691 Free PMC article. Review.
Imaging and CSF studies in the preclinical diagnosis of Alzheimer's disease.
de Leon MJ, Mosconi L, Blennow K, DeSanti S, Zinkowski R, Mehta PD, Pratico D, Tsui W, Saint Louis LA, Sobanska L, Brys M, Li Y, Rich K, Rinne J, Rusinek H. de Leon MJ, et al. Among authors: li y. Ann N Y Acad Sci. 2007 Feb;1097:114-45. doi: 10.1196/annals.1379.012. Ann N Y Acad Sci. 2007. PMID: 17413016 Review.
Reduced glucose uptake and Aβ in brain regions with hyperintensities in connected white matter.
Glodzik L, Kuceyeski A, Rusinek H, Tsui W, Mosconi L, Li Y, Osorio RS, Williams S, Randall C, Spector N, McHugh P, Murray J, Pirraglia E, Vallabhajosula S, Raj A, de Leon MJ. Glodzik L, et al. Among authors: li y. Neuroimage. 2014 Oct 15;100:684-691. doi: 10.1016/j.neuroimage.2014.06.060. Epub 2014 Jul 4. Neuroimage. 2014. PMID: 24999038 Free PMC article.
Decreased CSF clearance and increased brain amyloid in Alzheimer's disease.
Li Y, Rusinek H, Butler T, Glodzik L, Pirraglia E, Babich J, Mozley PD, Nehmeh S, Pahlajani S, Wang X, Tanzi EB, Zhou L, Strauss S, Carare RO, Theise N, Okamura N, de Leon MJ. Li Y, et al. Fluids Barriers CNS. 2022 Mar 14;19(1):21. doi: 10.1186/s12987-022-00318-y. Fluids Barriers CNS. 2022. PMID: 35287702 Free PMC article.
[1-11C]-Butanol Positron Emission Tomography reveals an impaired brain to nasal turbinates pathway in aging amyloid positive subjects.
Mehta NH, Wang X, Keil SA, Xi K, Zhou L, Lee K, Tan W, Spector E, Goldan A, Kelly J, Karakatsanis NA, Mozley PD, Nehmeh S, Chazen JL, Morin S, Babich J, Ivanidze J, Pahlajani S, Tanzi EB, Saint-Louis L, Butler T, Chen K, Rusinek H, Carare RO, Li Y, Chiang GC, de Leon MJ. Mehta NH, et al. Among authors: li y. Fluids Barriers CNS. 2024 Apr 2;21(1):30. doi: 10.1186/s12987-024-00530-y. Fluids Barriers CNS. 2024. PMID: 38566110 Free PMC article.
Longitudinal CSF and MRI biomarkers improve the diagnosis of mild cognitive impairment.
de Leon MJ, DeSanti S, Zinkowski R, Mehta PD, Pratico D, Segal S, Rusinek H, Li J, Tsui W, Saint Louis LA, Clark CM, Tarshish C, Li Y, Lair L, Javier E, Rich K, Lesbre P, Mosconi L, Reisberg B, Sadowski M, DeBernadis JF, Kerkman DJ, Hampel H, Wahlund LO, Davies P. de Leon MJ, et al. Among authors: li y, li j. Neurobiol Aging. 2006 Mar;27(3):394-401. doi: 10.1016/j.neurobiolaging.2005.07.003. Epub 2005 Aug 26. Neurobiol Aging. 2006. PMID: 16125823 Clinical Trial.
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