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Molecular mechanisms involved in muscarinic acetylcholine receptor-mediated G protein activation studied by insertion mutagenesis.
Liu J, Blin N, Conklin BR, Wess J. Liu J, et al. Among authors: wess j. J Biol Chem. 1996 Mar 15;271(11):6172-8. doi: 10.1074/jbc.271.11.6172. J Biol Chem. 1996. PMID: 8626406 Free article.
We have recently shown that a four-amino acid epitope (VTIL) on the m2 muscarinic receptor (corresponding to Val385, Thr386, Ile389, and Leu390) is essential for Gi/o coupling specificity and Gi/o activation (Liu, J., Conklin, B. R., Blin, N., Yun, J., and Wess
We have recently shown that a four-amino acid epitope (VTIL) on the m2 muscarinic receptor (corresponding to Val385, Thr386, Ile389, and Leu …
Molecular basis of receptor/G protein coupling selectivity studied by coexpression of wild type and mutant m2 muscarinic receptors with mutant G alpha(q) subunits.
Kostenis E, Conklin BR, Wess J. Kostenis E, et al. Among authors: wess j. Biochemistry. 1997 Feb 11;36(6):1487-95. doi: 10.1021/bi962554d. Biochemistry. 1997. PMID: 9063897
We could recently show that the m2 receptor can efficiently interact with mutant G protein alpha(q) subunits in which the last five amino acids were replaced with alpha(i2) or alpha(o) sequence [Liu, J., Conklin, B. R., Blin, N., Yun, J., & Wess, J
We could recently show that the m2 receptor can efficiently interact with mutant G protein alpha(q) subunits in which the last five amino ac …
348 results