Tenen DG - Search Results

1

A distal single nucleotide polymorphism alters long-range regulation of the PU.1 gene in acute myeloid leukemia.

Steidl U, Steidl C, Ebralidze A, Chapuy B, Han HJ, Will B, Rosenbauer F, Becker A, Wagner K, Koschmieder S, Kobayashi S, Costa DB, Schulz T, O'Brien KB, Verhaak RG, Delwel R, Haase D, Trümper L, Krauter J, Kohwi-Shigematsu T, Griesinger F, Tenen DG. Steidl U, et al. Among authors: tenen dg. J Clin Invest. 2007 Sep;117(9):2611-20. doi: 10.1172/JCI30525. J Clin Invest. 2007. PMID: 17694175 Free PMC article.

2

PU.1 (Spi-1) autoregulates its expression in myeloid cells.

Chen H, Ray-Gallet D, Zhang P, Hetherington CJ, Gonzalez DA, Zhang DE, Moreau-Gachelin F, Tenen DG. Chen H, et al. Among authors: tenen dg. Oncogene. 1995 Oct 19;11(8):1549-60. Oncogene. 1995. PMID: 7478579

3

Octamer binding factors and their coactivator can activate the murine PU.1 (spi-1) promoter.

Chen H, Zhang P, Radomska HS, Hetherington CJ, Zhang DE, Tenen DG. Chen H, et al. Among authors: tenen dg. J Biol Chem. 1996 Jun 28;271(26):15743-52. doi: 10.1074/jbc.271.26.15743. J Biol Chem. 1996. PMID: 8663022 Free article.

4

Use of RDA analysis of knockout mice to identify myeloid genes regulated in vivo by PU.1 and C/EBPalpha.

Iwama A, Zhang P, Darlington GJ, McKercher SR, Maki R, Tenen DG. Iwama A, et al. Among authors: tenen dg. Nucleic Acids Res. 1998 Jun 15;26(12):3034-43. doi: 10.1093/nar/26.12.3034. Nucleic Acids Res. 1998. PMID: 9611252 Free PMC article.

5

c-Jun is a JNK-independent coactivator of the PU.1 transcription factor.

Behre G, Whitmarsh AJ, Coghlan MP, Hoang T, Carpenter CL, Zhang DE, Davis RJ, Tenen DG. Behre G, et al. Among authors: tenen dg. J Biol Chem. 1999 Feb 19;274(8):4939-46. doi: 10.1074/jbc.274.8.4939. J Biol Chem. 1999. PMID: 9988737 Free article.

6

PU.1 inhibits GATA-1 function and erythroid differentiation by blocking GATA-1 DNA binding.

Zhang P, Zhang X, Iwama A, Yu C, Smith KA, Mueller BU, Narravula S, Torbett BE, Orkin SH, Tenen DG. Zhang P, et al. Among authors: tenen dg. Blood. 2000 Oct 15;96(8):2641-8. Blood. 2000. PMID: 11023493 Free article.

7

AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia.

Pabst T, Mueller BU, Harakawa N, Schoch C, Haferlach T, Behre G, Hiddemann W, Zhang DE, Tenen DG. Pabst T, et al. Among authors: tenen dg. Nat Med. 2001 Apr;7(4):444-51. doi: 10.1038/86515. Nat Med. 2001. PMID: 11283671

8

Regulation of the PU.1 gene by distal elements.

Li Y, Okuno Y, Zhang P, Radomska HS, Chen H, Iwasaki H, Akashi K, Klemsz MJ, McKercher SR, Maki RA, Tenen DG. Li Y, et al. Among authors: tenen dg. Blood. 2001 Nov 15;98(10):2958-65. doi: 10.1182/blood.v98.10.2958. Blood. 2001. PMID: 11698277 Free article.

9

Heterozygous PU.1 mutations are associated with acute myeloid leukemia.

Mueller BU, Pabst T, Osato M, Asou N, Johansen LM, Minden MD, Behre G, Hiddemann W, Ito Y, Tenen DG. Mueller BU, et al. Among authors: tenen dg. Blood. 2002 Aug 1;100(3):998-1007. doi: 10.1182/blood.v100.3.998. Blood. 2002. PMID: 12130514 Free article.

10

Disruption of differentiation in human cancer: AML shows the way.

Tenen DG. Tenen DG. Nat Rev Cancer. 2003 Feb;3(2):89-101. doi: 10.1038/nrc989. Nat Rev Cancer. 2003. PMID: 12563308 Review.

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