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VRX-03011, a novel 5-HT4 agonist, enhances memory and hippocampal acetylcholine efflux.
Mohler EG, Shacham S, Noiman S, Lezoualc'h F, Robert S, Gastineau M, Rutkowski J, Marantz Y, Dumuis A, Bockaert J, Gold PE, Ragozzino ME. Mohler EG, et al. Among authors: gastineau m. Neuropharmacology. 2007 Sep;53(4):563-73. doi: 10.1016/j.neuropharm.2007.06.016. Epub 2007 Jun 30. Neuropharmacology. 2007. PMID: 17692343
Crosstalk between Rap1 and Rac regulates secretion of sAPPalpha.
Maillet M, Robert SJ, Cacquevel M, Gastineau M, Vivien D, Bertoglio J, Zugaza JL, Fischmeister R, Lezoualc'h F. Maillet M, et al. Among authors: gastineau m. Nat Cell Biol. 2003 Jul;5(7):633-9. doi: 10.1038/ncb1007. Nat Cell Biol. 2003. PMID: 12819788
Functional studies of the 5'-untranslated region of human 5-HT4 receptor mRNA.
Maillet M, Gastineau M, Bochet P, Asselin-Labat ML, Morel E, Laverrière JN, Lompré AM, Fischmeister R, Lezoualc'h F. Maillet M, et al. Among authors: gastineau m. Biochem J. 2005 Apr 15;387(Pt 2):463-71. doi: 10.1042/BJ20040744. Biochem J. 2005. PMID: 15575821 Free PMC article.
Isolation of the serotoninergic 5-HT4(e) receptor from human heart and comparative analysis of its pharmacological profile in C6-glial and CHO cell lines.
Mialet J, Berque-Bestel I, Eftekhari P, Gastineau M, Giner M, Dahmoune Y, Donzeau-Gouge P, Hoebeke J, Langlois M, Sicsic S, Fischmeister R, Lezoualc'h F. Mialet J, et al. Among authors: gastineau m. Br J Pharmacol. 2000 Feb;129(4):771-81. doi: 10.1038/sj.bjp.0703101. Br J Pharmacol. 2000. PMID: 10683202 Free PMC article.
Anti-SSA/Ro52 autoantibodies blocking the cardiac 5-HT4 serotoninergic receptor could explain neonatal lupus congenital heart block.
Eftekhari P, Sallé L, Lezoualc'h F, Mialet J, Gastineau M, Briand JP, Isenberg DA, Fournié GJ, Argibay J, Fischmeister R, Muller S, Hoebeke J. Eftekhari P, et al. Among authors: gastineau m. Eur J Immunol. 2000 Oct;30(10):2782-90. doi: 10.1002/1521-4141(200010)30:10<2782::AID-IMMU2782>3.0.CO;2-9. Eur J Immunol. 2000. PMID: 11069058 Free article.
cAMP-binding protein Epac induces cardiomyocyte hypertrophy.
Morel E, Marcantoni A, Gastineau M, Birkedal R, Rochais F, Garnier A, Lompré AM, Vandecasteele G, Lezoualc'h F. Morel E, et al. Among authors: gastineau m. Circ Res. 2005 Dec 9;97(12):1296-304. doi: 10.1161/01.RES.0000194325.31359.86. Epub 2005 Nov 3. Circ Res. 2005. PMID: 16269655 Free article.
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