Sagartz JE - Search Results

1

The application of discovery toxicology and pathology towards the design of safer pharmaceutical lead candidates.

Kramer JA, Sagartz JE, Morris DL. Kramer JA, et al. Among authors: sagartz je. Nat Rev Drug Discov. 2007 Aug;6(8):636-49. doi: 10.1038/nrd2378. Nat Rev Drug Discov. 2007. PMID: 17643090 Review.

2

The pathologist and toxicologist in pharmaceutical product discovery.

Alden CL, Sagartz JE, Smith PF, Wilson AG, Bunch RT, Morris DL. Alden CL, et al. Among authors: sagartz je. Toxicol Pathol. 1999 Jan-Feb;27(1):104-6. doi: 10.1177/019262339902700119. Toxicol Pathol. 1999. PMID: 10367682 Review.

3

Acute lymphoid and gastrointestinal toxicity induced by selective p38alpha map kinase and map kinase-activated protein kinase-2 (MK2) inhibitors in the dog.

Morris DL, O'Neil SP, Devraj RV, Portanova JP, Gilles RW, Gross CJ, Curtiss SW, Komocsar WJ, Garner DS, Happa FA, Kraus LJ, Nikula KJ, Monahan JB, Selness SR, Galluppi GR, Shevlin KM, Kramer JA, Walker JK, Messing DM, Anderson DR, Mourey RJ, Whiteley LO, Daniels JS, Yang JZ, Rowlands PC, Alden CL, Davis JW 2nd, Sagartz JE. Morris DL, et al. Among authors: sagartz je. Toxicol Pathol. 2010 Jun;38(4):606-18. doi: 10.1177/0192623310367807. Epub 2010 May 6. Toxicol Pathol. 2010. PMID: 20448081

4

Phenobarbital does not promote hepatic tumorigenesis in a twenty-six-week bioassay in p53 heterozygous mice.

Sagartz JE, Curtiss SW, Bunch RT, Davila JC, Morris DL, Alden CL. Sagartz JE, et al. Toxicol Pathol. 1998 Jul-Aug;26(4):492-500. doi: 10.1177/019262339802600405. Toxicol Pathol. 1998. PMID: 9715508

5

P53+/- hemizygous knockout mouse: overview of available data.

Storer RD, French JE, Haseman J, Hajian G, LeGrand EK, Long GG, Mixson LA, Ochoa R, Sagartz JE, Soper KA. Storer RD, et al. Among authors: sagartz je. Toxicol Pathol. 2001;29 Suppl:30-50. doi: 10.1080/019262301753178465. Toxicol Pathol. 2001. PMID: 11695560 Review.

6

Neonatal mouse model: review of methods and results.

McClain RM, Keller D, Casciano D, Fu P, MacDonald J, Popp J, Sagartz J. McClain RM, et al. Toxicol Pathol. 2001;29 Suppl:128-37. doi: 10.1080/019262301753178537. Toxicol Pathol. 2001. PMID: 11695548 Review.

7

NSAID-induced acute phase response is due to increased intestinal permeability and characterized by early and consistent alterations in hepatic gene expression.

Tugendreich S, Pearson CI, Sagartz J, Jarnagin K, Kolaja K. Tugendreich S, et al. Toxicol Pathol. 2006;34(2):168-79. doi: 10.1080/01926230600611752. Toxicol Pathol. 2006. PMID: 16642600

8

MBP-1 inhibits breast cancer growth and metastasis in immunocompetent mice.

Kanda T, Raychoudhuri A, Steele R, Sagartz JE, West C, Ray RB. Kanda T, et al. Among authors: sagartz je. Cancer Res. 2009 Dec 15;69(24):9354-9. doi: 10.1158/0008-5472.CAN-09-2974. Cancer Res. 2009. PMID: 19934312

9

Autoimmune gastritis mediated by CD4+ T cells promotes the development of gastric cancer.

Nguyen TL, Khurana SS, Bellone CJ, Capoccia BJ, Sagartz JE, Kesman RA Jr, Mills JC, DiPaolo RJ. Nguyen TL, et al. Among authors: sagartz je. Cancer Res. 2013 Apr 1;73(7):2117-26. doi: 10.1158/0008-5472.CAN-12-3957. Epub 2013 Feb 1. Cancer Res. 2013. PMID: 23378345 Free PMC article.

10

Phagocytosis of fluorescent beads by rat thyroid follicular cells (FRTL-5): comparison with iodide trapping as an index of functional activity of thyrocytes in vitro.

Sagartz JE, Ozaki A, Capen CC. Sagartz JE, et al. Toxicol Pathol. 1995 Nov-Dec;23(6):635-43. doi: 10.1177/019262339502300601. Toxicol Pathol. 1995. PMID: 8772249

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