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Development and validation of a LC-MS/MS method for the determination of the novel oral 1,14 substituted taxane derivatives, IDN 5738 and IDN 5839, in mouse plasma and its application to the pharmacokinetic study.
Marangon E, Falcioni C, Manzotti C, Fontana G, D'Incalci M, Zucchetti M. Marangon E, et al. Among authors: falcioni c. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Dec 15;877(32):4147-53. doi: 10.1016/j.jchromb.2009.10.016. Epub 2009 Oct 23. J Chromatogr B Analyt Technol Biomed Life Sci. 2009. PMID: 19906566
Pharmacokinetics and metabolism in mice of IDN 5390 (13-(N-Boc-3-i-butylisoserinoyl)-C-7,8-seco-10-deacetylbaccatin III), a new oral c-seco-taxane derivative with antiangiogenic property effective on paclitaxel-resistant tumors.
Frapolli R, Marangon E, Zaffaroni M, Colombo T, Falcioni C, Bagnati R, Simone M, D'Incalci M, Manzotti C, Fontana G, Morazzoni P, Zucchetti M. Frapolli R, et al. Among authors: falcioni c. Drug Metab Dispos. 2006 Dec;34(12):2028-35. doi: 10.1124/dmd.106.012153. Epub 2006 Sep 8. Drug Metab Dispos. 2006. PMID: 16963486
Dietary agent indole-3-carbinol protects female rats against the hepatotoxicity of the antitumor drug ET-743 (trabectidin) without compromising efficacy in a rat mammary carcinoma.
Donald S, Verschoyle RD, Greaves P, Colombo T, Zucchetti M, Falcioni C, Zaffaroni M, D'Incalci M, Manson MM, Jimeno J, Steward WP, Gescher AJ. Donald S, et al. Among authors: falcioni c. Int J Cancer. 2004 Oct 10;111(6):961-7. doi: 10.1002/ijc.20356. Int J Cancer. 2004. PMID: 15300810 Free article.