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Phase I and pharmacokinetic study of the oral farnesyltransferase inhibitor lonafarnib administered twice daily to pediatric patients with advanced central nervous system tumors using a modified continuous reassessment method: a Pediatric Brain Tumor Consortium Study.
Kieran MW, Packer RJ, Onar A, Blaney SM, Phillips P, Pollack IF, Geyer JR, Gururangan S, Banerjee A, Goldman S, Turner CD, Belasco JB, Broniscer A, Zhu Y, Frank E, Kirschmeier P, Statkevich P, Yver A, Boyett JM, Kun LE. Kieran MW, et al. Among authors: belasco jb. J Clin Oncol. 2007 Jul 20;25(21):3137-43. doi: 10.1200/JCO.2006.09.4243. J Clin Oncol. 2007. PMID: 17634493 Clinical Trial.
Phase 2 randomized, flexible crossover, double-blinded, placebo-controlled trial of the farnesyltransferase inhibitor tipifarnib in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas.
Widemann BC, Dombi E, Gillespie A, Wolters PL, Belasco J, Goldman S, Korf BR, Solomon J, Martin S, Salzer W, Fox E, Patronas N, Kieran MW, Perentesis JP, Reddy A, Wright JJ, Kim A, Steinberg SM, Balis FM. Widemann BC, et al. Neuro Oncol. 2014 May;16(5):707-18. doi: 10.1093/neuonc/nou004. Epub 2014 Feb 4. Neuro Oncol. 2014. PMID: 24500418 Free PMC article. Clinical Trial.
Neuroplastic Response After Radiation Therapy for Pediatric Brain Tumors: A Pilot Study.
Armstrong CL, Fisher MJ, Li Y, Lustig RA, Belasco JB, Minturn JE, Hill-Kayser CE, Batra S, Phillips PC. Armstrong CL, et al. Among authors: belasco jb. Int J Radiat Oncol Biol Phys. 2016 Jul 1;95(3):991-998. doi: 10.1016/j.ijrobp.2016.01.013. Epub 2016 Mar 17. Int J Radiat Oncol Biol Phys. 2016. PMID: 27302514 Clinical Trial.
54 results