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971 results

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Mechanism of the anti-obesity effects induced by a novel melanin-concentrating hormone 1-receptor antagonist in mice.
Ito M, Ishihara A, Gomori A, Matsushita H, Ito M, Metzger JM, Marsh DJ, Haga Y, Iwaasa H, Tokita S, Takenaga N, Sato N, MacNeil DJ, Moriya M, Kanatani A. Ito M, et al. Among authors: matsushita h. Br J Pharmacol. 2010 Jan 1;159(2):374-83. doi: 10.1111/j.1476-5381.2009.00536.x. Epub 2009 Dec 10. Br J Pharmacol. 2010. PMID: 20015294 Free PMC article.
Characterization of MCH-mediated obesity in mice.
Ito M, Gomori A, Ishihara A, Oda Z, Mashiko S, Matsushita H, Yumoto M, Ito M, Sano H, Tokita S, Moriya M, Iwaasa H, Kanatani A. Ito M, et al. Among authors: matsushita h. Am J Physiol Endocrinol Metab. 2003 May;284(5):E940-5. doi: 10.1152/ajpendo.00529.2002. Epub 2003 Jan 28. Am J Physiol Endocrinol Metab. 2003. PMID: 12554598 Free article.
A pair-feeding study reveals that a Y5 antagonist causes weight loss in diet-induced obese mice by modulating food intake and energy expenditure.
Mashiko S, Ishihara A, Iwaasa H, Sano H, Ito J, Gomori A, Oda Z, Moriya R, Matsushita H, Jitsuoka M, Okamoto O, MacNeil DJ, Van der Ploeg LH, Fukami T, Kanatani A. Mashiko S, et al. Among authors: matsushita h. Mol Pharmacol. 2007 Feb;71(2):602-8. doi: 10.1124/mol.106.029991. Epub 2006 Nov 14. Mol Pharmacol. 2007. PMID: 17105869
Melanin-concentrating hormone 1-receptor antagonist suppresses body weight gain correlated with high receptor occupancy levels in diet-induced obesity mice.
Ito M, Ishihara A, Gomori A, Egashira S, Matsushita H, Mashiko S, Ito J, Ito M, Nakase K, Haga Y, Iwaasa H, Suzuki T, Ohtake N, Moriya M, Sato N, MacNeil DJ, Takenaga N, Tokita S, Kanatani A. Ito M, et al. Among authors: matsushita h. Eur J Pharmacol. 2009 Dec 10;624(1-3):77-83. doi: 10.1016/j.ejphar.2009.10.004. Epub 2009 Oct 18. Eur J Pharmacol. 2009. PMID: 19836369
A neuropeptide Y Y5 antagonist selectively ameliorates body weight gain and associated parameters in diet-induced obese mice.
Ishihara A, Kanatani A, Mashiko S, Tanaka T, Hidaka M, Gomori A, Iwaasa H, Murai N, Egashira S, Murai T, Mitobe Y, Matsushita H, Okamoto O, Sato N, Jitsuoka M, Fukuroda T, Ohe T, Guan X, MacNeil DJ, Van der Ploeg LH, Nishikibe M, Ishii Y, Ihara M, Fukami T. Ishihara A, et al. Among authors: matsushita h. Proc Natl Acad Sci U S A. 2006 May 2;103(18):7154-8. doi: 10.1073/pnas.0510320103. Epub 2006 Apr 24. Proc Natl Acad Sci U S A. 2006. PMID: 16636293 Free PMC article.
Effects of a novel Y5 antagonist in obese mice: combination with food restriction or sibutramine.
Mashiko S, Ishihara A, Iwaasa H, Moriya R, Kitazawa H, Mitobe Y, Ito J, Gomori A, Matsushita H, Takahashi T, MacNeil DJ, Van der Ploeg LH, Fukami T, Kanatani A. Mashiko S, et al. Among authors: matsushita h. Obesity (Silver Spring). 2008 Jul;16(7):1510-5. doi: 10.1038/oby.2008.223. Epub 2008 Apr 10. Obesity (Silver Spring). 2008. PMID: 18421274 Free article.
971 results