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Mechanisms of Nitrosamine Mutagenicity and Their Relationship to Rodent Carcinogenic Potency.
Snodin DJ, Trejo-Martin A, Ponting DJ, Smith GF, Czich A, Cross K, Custer L, Elloway J, Greene N, Kalgutkar AS, Stalford SA, Tennant RE, Vock E, Zalewski A, Ziegler V, Dobo KL. Snodin DJ, et al. Among authors: dobo kl. Chem Res Toxicol. 2024 Feb 19;37(2):181-198. doi: 10.1021/acs.chemrestox.3c00327. Epub 2024 Feb 5. Chem Res Toxicol. 2024. PMID: 38316048 Review.
Permitted daily exposure limits for noteworthy N-nitrosamines.
Johnson GE, Dobo K, Gollapudi B, Harvey J, Kenny J, Kenyon M, Lynch A, Minocherhomji S, Nicolette J, Thybaud V, Wheeldon R, Zeller A. Johnson GE, et al. Among authors: dobo k. Environ Mol Mutagen. 2021 Jun;62(5):293-305. doi: 10.1002/em.22446. Environ Mol Mutagen. 2021. PMID: 34089278
Management of pharmaceutical ICH M7 (Q)SAR predictions - The impact of model updates.
Hasselgren C, Bercu J, Cayley A, Cross K, Glowienke S, Kruhlak N, Muster W, Nicolette J, Reddy MV, Saiakhov R, Dobo K. Hasselgren C, et al. Among authors: dobo k. Regul Toxicol Pharmacol. 2020 Dec;118:104807. doi: 10.1016/j.yrtph.2020.104807. Epub 2020 Oct 13. Regul Toxicol Pharmacol. 2020. PMID: 33058939 Free PMC article.
In Vivo Mutagenicity Testing of Arylboronic Acids and Esters.
Masuda-Herrera MJ, Dobo KL, Kenyon MO, Kenny JD, Galloway SM, Escobar PA, Reddy MV, Jolly RA, Trejo-Martin A, Brown C, Mckeon M, Young M, Bruce S, Pant K, Dutta A, Kulkarni R, Bercu JP. Masuda-Herrera MJ, et al. Among authors: dobo kl. Environ Mol Mutagen. 2019 Dec;60(9):766-777. doi: 10.1002/em.22320. Epub 2019 Aug 17. Environ Mol Mutagen. 2019. PMID: 31335992
Genetic toxicology in silico protocol.
Hasselgren C, Ahlberg E, Akahori Y, Amberg A, Anger LT, Atienzar F, Auerbach S, Beilke L, Bellion P, Benigni R, Bercu J, Booth ED, Bower D, Brigo A, Cammerer Z, Cronin MTD, Crooks I, Cross KP, Custer L, Dobo K, Doktorova T, Faulkner D, Ford KA, Fortin MC, Frericks M, Gad-McDonald SE, Gellatly N, Gerets H, Gervais V, Glowienke S, Van Gompel J, Harvey JS, Hillegass J, Honma M, Hsieh JH, Hsu CW, Barton-Maclaren TS, Johnson C, Jolly R, Jones D, Kemper R, Kenyon MO, Kruhlak NL, Kulkarni SA, Kümmerer K, Leavitt P, Masten S, Miller S, Moudgal C, Muster W, Paulino A, Lo Piparo E, Powley M, Quigley DP, Reddy MV, Richarz AN, Schilter B, Snyder RD, Stavitskaya L, Stidl R, Szabo DT, Teasdale A, Tice RR, Trejo-Martin A, Vuorinen A, Wall BA, Watts P, White AT, Wichard J, Witt KL, Woolley A, Woolley D, Zwickl C, Myatt GJ. Hasselgren C, et al. Among authors: dobo k. Regul Toxicol Pharmacol. 2019 Oct;107:104403. doi: 10.1016/j.yrtph.2019.104403. Epub 2019 Jun 11. Regul Toxicol Pharmacol. 2019. PMID: 31195068 Free PMC article.
2-Hydroxypyridine N-Oxide is not genotoxic in vivo.
Dobo KL, Coffing S, Gunther WC, Homiski M. Dobo KL, et al. Environ Mol Mutagen. 2019 Aug;60(7):588-593. doi: 10.1002/em.22294. Epub 2019 May 23. Environ Mol Mutagen. 2019. PMID: 31001845
46 results