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9-cis-Retinoic acid (9cRA), a retinoid X receptor (RXR) ligand, exerts immunosuppressive effects on dendritic cells by RXR-dependent activation: inhibition of peroxisome proliferator-activated receptor gamma blocks some of the 9cRA activities, and precludes them to mature phenotype development.
Zapata-Gonzalez F, Rueda F, Petriz J, Domingo P, Villarroya F, de Madariaga A, Domingo JC. Zapata-Gonzalez F, et al. Among authors: rueda f. J Immunol. 2007 May 15;178(10):6130-9. doi: 10.4049/jimmunol.178.10.6130. J Immunol. 2007. PMID: 17475839
Human dendritic cell activities are modulated by the omega-3 fatty acid, docosahexaenoic acid, mainly through PPAR(gamma):RXR heterodimers: comparison with other polyunsaturated fatty acids.
Zapata-Gonzalez F, Rueda F, Petriz J, Domingo P, Villarroya F, Diaz-Delfin J, de Madariaga MA, Domingo JC. Zapata-Gonzalez F, et al. Among authors: rueda f. J Leukoc Biol. 2008 Oct;84(4):1172-82. doi: 10.1189/jlb.1007688. Epub 2008 Jul 16. J Leukoc Biol. 2008. PMID: 18632990
Targeting nanoparticles to dendritic cells for immunotherapy.
Cruz LJ, Tacken PJ, Rueda F, Domingo JC, Albericio F, Figdor CG. Cruz LJ, et al. Among authors: rueda f. Methods Enzymol. 2012;509:143-63. doi: 10.1016/B978-0-12-391858-1.00008-3. Methods Enzymol. 2012. PMID: 22568905 Review.
127 results