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Mitochondrial targeting of quinones: therapeutic implications.
Cochemé HM, Kelso GF, James AM, Ross MF, Trnka J, Mahendiran T, Asin-Cayuela J, Blaikie FH, Manas AR, Porteous CM, Adlam VJ, Smith RA, Murphy MP. Cochemé HM, et al. Mitochondrion. 2007 Jun;7 Suppl:S94-102. doi: 10.1016/j.mito.2007.02.007. Epub 2007 Mar 16. Mitochondrion. 2007. PMID: 17449335 Review.
Superoxide activates uncoupling proteins by generating carbon-centered radicals and initiating lipid peroxidation: studies using a mitochondria-targeted spin trap derived from alpha-phenyl-N-tert-butylnitrone.
Murphy MP, Echtay KS, Blaikie FH, Asin-Cayuela J, Cocheme HM, Green K, Buckingham JA, Taylor ER, Hurrell F, Hughes G, Miwa S, Cooper CE, Svistunenko DA, Smith RA, Brand MD. Murphy MP, et al. Among authors: cocheme hm. J Biol Chem. 2003 Dec 5;278(49):48534-45. doi: 10.1074/jbc.M308529200. Epub 2003 Sep 12. J Biol Chem. 2003. PMID: 12972420 Free article.
Consequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type mice.
Rodriguez-Cuenca S, Cochemé HM, Logan A, Abakumova I, Prime TA, Rose C, Vidal-Puig A, Smith AC, Rubinsztein DC, Fearnley IM, Jones BA, Pope S, Heales SJ, Lam BY, Neogi SG, McFarlane I, James AM, Smith RA, Murphy MP. Rodriguez-Cuenca S, et al. Among authors: cocheme hm. Free Radic Biol Med. 2010 Jan 1;48(1):161-72. doi: 10.1016/j.freeradbiomed.2009.10.039. Epub 2009 Oct 23. Free Radic Biol Med. 2010. PMID: 19854266
Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix.
Cochemé HM, Quin C, McQuaker SJ, Cabreiro F, Logan A, Prime TA, Abakumova I, Patel JV, Fearnley IM, James AM, Porteous CM, Smith RA, Saeed S, Carré JE, Singer M, Gems D, Hartley RC, Partridge L, Murphy MP. Cochemé HM, et al. Cell Metab. 2011 Mar 2;13(3):340-50. doi: 10.1016/j.cmet.2011.02.003. Cell Metab. 2011. PMID: 21356523 Free PMC article.
Mitochondrial redox signalling at a glance.
Collins Y, Chouchani ET, James AM, Menger KE, Cochemé HM, Murphy MP. Collins Y, et al. Among authors: cocheme hm. J Cell Sci. 2012 Feb 15;125(Pt 4):801-6. doi: 10.1242/jcs.098475. J Cell Sci. 2012. PMID: 22448036 No abstract available.
40 results