Nguyen D - Search Results

1

Structural basis for a high affinity inhibitor bound to protein kinase MK2.

Hillig RC, Eberspaecher U, Monteclaro F, Huber M, Nguyen D, Mengel A, Muller-Tiemann B, Egner U. Hillig RC, et al. Among authors: nguyen d. J Mol Biol. 2007 Jun 8;369(3):735-45. doi: 10.1016/j.jmb.2007.03.004. Epub 2007 Mar 12. J Mol Biol. 2007. PMID: 17449059

2

A crystallographic fragment screen identifies cinnamic acid derivatives as starting points for potent Pim-1 inhibitors.

Schulz MN, Fanghänel J, Schäfer M, Badock V, Briem H, Boemer U, Nguyen D, Husemann M, Hillig RC. Schulz MN, et al. Among authors: nguyen d. Acta Crystallogr D Biol Crystallogr. 2011 Mar;67(Pt 3):156-66. doi: 10.1107/S0907444910054144. Epub 2011 Feb 15. Acta Crystallogr D Biol Crystallogr. 2011. PMID: 21358046

3

Discovery and Characterization of the Potent and Highly Selective (Piperidin-4-yl)pyrido[3,2- d]pyrimidine Based in Vitro Probe BAY-885 for the Kinase ERK5.

Nguyen D, Lemos C, Wortmann L, Eis K, Holton SJ, Boemer U, Moosmayer D, Eberspaecher U, Weiske J, Lechner C, Prechtl S, Suelzle D, Siegel F, Prinz F, Lesche R, Nicke B, Nowak-Reppel K, Himmel H, Mumberg D, von Nussbaum F, Nising CF, Bauser M, Haegebarth A. Nguyen D, et al. J Med Chem. 2019 Jan 24;62(2):928-940. doi: 10.1021/acs.jmedchem.8b01606. Epub 2019 Jan 9. J Med Chem. 2019. PMID: 30563338

4

Computationally Empowered Workflow Identifies Novel Covalent Allosteric Binders for KRAS^G12C.

Mortier J, Friberg A, Badock V, Moosmayer D, Schroeder J, Steigemann P, Siegel F, Gradl S, Bauser M, Hillig RC, Briem H, Eis K, Bader B, Nguyen D, Christ CD. Mortier J, et al. Among authors: nguyen d. ChemMedChem. 2020 May 19;15(10):827-832. doi: 10.1002/cmdc.201900727. Epub 2020 Apr 1. ChemMedChem. 2020. PMID: 32237114 Free PMC article.

5

Treating Cancer by Spindle Assembly Checkpoint Abrogation: Discovery of Two Clinical Candidates, BAY 1161909 and BAY 1217389, Targeting MPS1 Kinase.

Schulze VK, Klar U, Kosemund D, Wengner AM, Siemeister G, Stöckigt D, Neuhaus R, Lienau P, Bader B, Prechtl S, Holton SJ, Briem H, Marquardt T, Schirok H, Jautelat R, Bohlmann R, Nguyen D, Fernández-Montalván AE, Bömer U, Eberspaecher U, Brüning M, Döhr O, Raschke M, Kreft B, Mumberg D, Ziegelbauer K, Brands M, von Nussbaum F, Koppitz M. Schulze VK, et al. Among authors: nguyen d. J Med Chem. 2020 Aug 13;63(15):8025-8042. doi: 10.1021/acs.jmedchem.9b02035. Epub 2020 Apr 27. J Med Chem. 2020. PMID: 32338514

6

BAY-069, a Novel (Trifluoromethyl)pyrimidinedione-Based BCAT1/2 Inhibitor and Chemical Probe.

Günther J, Hillig RC, Zimmermann K, Kaulfuss S, Lemos C, Nguyen D, Rehwinkel H, Habgood M, Lechner C, Neuhaus R, Ganzer U, Drewes M, Chai J, Bouché L. Günther J, et al. Among authors: nguyen d. J Med Chem. 2022 Nov 10;65(21):14366-14390. doi: 10.1021/acs.jmedchem.2c00441. Epub 2022 Oct 19. J Med Chem. 2022. PMID: 36261130 Free PMC article.

7

In vivo characterization of estrogen receptor modulators with reduced genomic versus nongenomic activity in vitro.

Otto C, Fuchs I, Altmann H, Klewer M, Schwarz G, Bohlmann R, Nguyen D, Zorn L, Vonk R, Prelle K, Osterman T, Malmström C, Fritzemeier KH. Otto C, et al. Among authors: nguyen d. J Steroid Biochem Mol Biol. 2008 Jul;111(1-2):95-100. doi: 10.1016/j.jsbmb.2008.05.003. Epub 2008 Jul 7. J Steroid Biochem Mol Biol. 2008. PMID: 18606537

8

Structural Evidence for Isoform-Selective Allosteric Inhibition of Lactate Dehydrogenase A.

Friberg A, Rehwinkel H, Nguyen D, Pütter V, Quanz M, Weiske J, Eberspächer U, Heisler I, Langer G. Friberg A, et al. Among authors: nguyen d. ACS Omega. 2020 May 27;5(22):13034-13041. doi: 10.1021/acsomega.0c00715. eCollection 2020 Jun 9. ACS Omega. 2020. PMID: 32548488 Free PMC article.

9

High Throughput FISH Screening Identifies Small Molecules That Modulate Oncogenic lncRNA MALAT1 via GSK3B and hnRNPs.

Zablowsky N, Farack L, Rofall S, Kramer J, Meyer H, Nguyen D, Ulrich AKC, Bader B, Steigemann P. Zablowsky N, et al. Among authors: nguyen d. Noncoding RNA. 2023 Jan 3;9(1):2. doi: 10.3390/ncrna9010002. Noncoding RNA. 2023. PMID: 36649031 Free PMC article.

10

Real-Time Diagnosis and Monitoring of Biofilm and Corrosion Layer Formation on Different Water Pipe Materials Using Non-Invasive Imaging Methods.

Im HR, Im SJ, Nguyen DV, Jeong SP, Jang A. Im HR, et al. Among authors: nguyen dv. Chemosphere. 2024 Jun 8:142577. doi: 10.1016/j.chemosphere.2024.142577. Online ahead of print. Chemosphere. 2024. PMID: 38857632

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