de Strooper B - Search Results

1

Familial Alzheimer disease-linked mutations specifically disrupt Ca2+ leak function of presenilin 1.

Nelson O, Tu H, Lei T, Bentahir M, de Strooper B, Bezprozvanny I. Nelson O, et al. Among authors: de strooper b. J Clin Invest. 2007 May;117(5):1230-9. doi: 10.1172/JCI30447. Epub 2007 Apr 12. J Clin Invest. 2007. PMID: 17431506 Free PMC article.

2

Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations.

Tu H, Nelson O, Bezprozvanny A, Wang Z, Lee SF, Hao YH, Serneels L, De Strooper B, Yu G, Bezprozvanny I. Tu H, et al. Among authors: de strooper b. Cell. 2006 Sep 8;126(5):981-93. doi: 10.1016/j.cell.2006.06.059. Cell. 2006. PMID: 16959576 Free PMC article.

3

Mutagenesis mapping of the presenilin 1 calcium leak conductance pore.

Nelson O, Supnet C, Tolia A, Horré K, De Strooper B, Bezprozvanny I. Nelson O, et al. Among authors: de strooper b. J Biol Chem. 2011 Jun 24;286(25):22339-47. doi: 10.1074/jbc.M111.243063. Epub 2011 Apr 29. J Biol Chem. 2011. PMID: 21531718 Free PMC article.

4

Role of presenilins in neuronal calcium homeostasis.

Zhang H, Sun S, Herreman A, De Strooper B, Bezprozvanny I. Zhang H, et al. Among authors: de strooper b. J Neurosci. 2010 Jun 23;30(25):8566-80. doi: 10.1523/JNEUROSCI.1554-10.2010. J Neurosci. 2010. PMID: 20573903 Free PMC article.

5

Response to Shilling et al. (10.1074/jbc.M111.300491).

Bezprozvanny I, Supnet C, Sun S, Zhang H, De Strooper B. Bezprozvanny I, et al. Among authors: de strooper b. J Biol Chem. 2012 Jun 8;287(24):20469; author reply 20470. doi: 10.1074/jbc.L112.356790. J Biol Chem. 2012. PMID: 22685228 Free PMC article. No abstract available.

6

Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms.

Bentahir M, Nyabi O, Verhamme J, Tolia A, Horré K, Wiltfang J, Esselmann H, De Strooper B. Bentahir M, et al. Among authors: de strooper b. J Neurochem. 2006 Feb;96(3):732-42. doi: 10.1111/j.1471-4159.2005.03578.x. Epub 2006 Jan 9. J Neurochem. 2006. PMID: 16405513 Free article.

7

The discrepancy between presenilin subcellular localization and gamma-secretase processing of amyloid precursor protein.

Cupers P, Bentahir M, Craessaerts K, Orlans I, Vanderstichele H, Saftig P, De Strooper B, Annaert W. Cupers P, et al. Among authors: de strooper b. J Cell Biol. 2001 Aug 20;154(4):731-40. doi: 10.1083/jcb.200104045. Epub 2001 Aug 13. J Cell Biol. 2001. PMID: 11502763 Free PMC article.

8

Presenilins mutated at Asp-257 or Asp-385 restore Pen-2 expression and Nicastrin glycosylation but remain catalytically inactive in the absence of wild type Presenilin.

Nyabi O, Bentahir M, Horré K, Herreman A, Gottardi-Littell N, Van Broeckhoven C, Merchiers P, Spittaels K, Annaert W, De Strooper B. Nyabi O, et al. Among authors: de strooper b. J Biol Chem. 2003 Oct 31;278(44):43430-6. doi: 10.1074/jbc.M306957200. Epub 2003 Jul 28. J Biol Chem. 2003. PMID: 12885769 Free article.

9

Analysis of the gamma-secretase interactome and validation of its association with tetraspanin-enriched microdomains.

Wakabayashi T, Craessaerts K, Bammens L, Bentahir M, Borgions F, Herdewijn P, Staes A, Timmerman E, Vandekerckhove J, Rubinstein E, Boucheix C, Gevaert K, De Strooper B. Wakabayashi T, et al. Among authors: de strooper b. Nat Cell Biol. 2009 Nov;11(11):1340-6. doi: 10.1038/ncb1978. Epub 2009 Oct 18. Nat Cell Biol. 2009. PMID: 19838174

10

Loss-of-function presenilin mutations in Alzheimer disease. Talking Point on the role of presenilin mutations in Alzheimer disease.

De Strooper B. De Strooper B. EMBO Rep. 2007 Feb;8(2):141-6. doi: 10.1038/sj.embor.7400897. EMBO Rep. 2007. PMID: 17268505 Free PMC article. Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

396 results

Search Page