Tosha T - Search Results

1

Unique peroxidase reaction mechanism in prostaglandin endoperoxide H synthase-2: compound I in prostaglandin endoperoxide H synthase-2 can be formed without assistance by distal glutamine residue.

Ichimura S, Uchida T, Taniguchi S, Hira S, Tosha T, Morishima I, Kitagawa T, Ishimori K. Ichimura S, et al. Among authors: tosha t. J Biol Chem. 2007 Jun 1;282(22):16681-90. doi: 10.1074/jbc.M610785200. Epub 2007 Apr 1. J Biol Chem. 2007. PMID: 17403665 Free article.

2

Molecular mechanism of the electron transfer reaction in cytochrome P450(cam)--putidaredoxin: roles of glutamine 360 at the heme proximal site.

Tosha T, Yoshioka S, Hori H, Takahashi S, Ishimori K, Morishima I. Tosha T, et al. Biochemistry. 2002 Nov 26;41(47):13883-93. doi: 10.1021/bi0261037. Biochemistry. 2002. PMID: 12437345

3

Roles of the proximal hydrogen bonding network in cytochrome P450cam-catalyzed oxygenation.

Yoshioka S, Tosha T, Takahashi S, Ishimori K, Hori H, Morishima I. Yoshioka S, et al. Among authors: tosha t. J Am Chem Soc. 2002 Dec 11;124(49):14571-9. doi: 10.1021/ja0265409. J Am Chem Soc. 2002. PMID: 12465966

4

NMR study on the structural changes of cytochrome P450cam upon the complex formation with putidaredoxin. Functional significance of the putidaredoxin-induced structural changes.

Tosha T, Yoshioka S, Takahashi S, Ishimori K, Shimada H, Morishima I. Tosha T, et al. J Biol Chem. 2003 Oct 10;278(41):39809-21. doi: 10.1074/jbc.M304265200. Epub 2003 Jul 2. J Biol Chem. 2003. PMID: 12842870 Free article.

5

Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding.

Nagano S, Tosha T, Ishimori K, Morishima I, Poulos TL. Nagano S, et al. Among authors: tosha t. J Biol Chem. 2004 Oct 8;279(41):42844-9. doi: 10.1074/jbc.M404217200. Epub 2004 Jul 21. J Biol Chem. 2004. PMID: 15269210 Free article.

Pdx binding also enhances the camphor monooxygenation reaction (Nagano, S., Shimada, H., Tarumi, A., Hishiki, T., Kimata-Ariga, Y., Egawa, T., Suematsu, M., Park, S.-Y., Adachi, S., Shiro, Y., and Ishimura, Y. (2003) Biochemistry 42, 14507-14514). These effects are …

Pdx binding also enhances the camphor monooxygenation reaction (Nagano, S., Shimada, H., Tarumi, A., Hishiki, T., Kimata-Ariga, Y., E …

6

L358P mutation on cytochrome P450cam simulates structural changes upon putidaredoxin binding: the structural changes trigger electron transfer to oxy-P450cam from electron donors.

Tosha T, Yoshioka S, Ishimori K, Morishima I. Tosha T, et al. J Biol Chem. 2004 Oct 8;279(41):42836-43. doi: 10.1074/jbc.M404216200. Epub 2004 Jul 21. J Biol Chem. 2004. PMID: 15269211 Free article.

7

Structural and functional characterization of "laboratory evolved" cytochrome P450cam mutants showing enhanced naphthalene oxygenation activity.

Matsuura K, Tosha T, Yoshioka S, Takahashi S, Ishimori K, Morishima I. Matsuura K, et al. Among authors: tosha t. Biochem Biophys Res Commun. 2004 Oct 29;323(4):1209-15. doi: 10.1016/j.bbrc.2004.08.221. Biochem Biophys Res Commun. 2004. PMID: 15451425

8

Structural diversities of active site in clinical azole-bound forms between sterol 14alpha-demethylases (CYP51s) from human and Mycobacterium tuberculosis.

Matsuura K, Yoshioka S, Tosha T, Hori H, Ishimori K, Kitagawa T, Morishima I, Kagawa N, Waterman MR. Matsuura K, et al. Among authors: tosha t. J Biol Chem. 2005 Mar 11;280(10):9088-96. doi: 10.1074/jbc.M413042200. Epub 2004 Dec 20. J Biol Chem. 2005. PMID: 15611056 Free article.

9

Synthesis and reactivity of a (mu-1,1-hydroperoxo)(mu-hydroxo)dicopper(II) complex: ligand hydroxylation by a bridging hydroperoxo ligand.

Itoh K, Hayashi H, Furutachi H, Matsumoto T, Nagatomo S, Tosha T, Terada S, Fujinami S, Suzuki M, Kitagawa T. Itoh K, et al. Among authors: tosha t. J Am Chem Soc. 2005 Apr 13;127(14):5212-23. doi: 10.1021/ja047437h. J Am Chem Soc. 2005. PMID: 15810857

10

Structure and dioxygen-reactivity of copper(I) complexes supported by bis(6-methylpyridin-2-ylmethyl)amine tridentate ligands.

Osako T, Terada S, Tosha T, Nagatomo S, Furutachi H, Fujinami S, Kitagawa T, Suzuki M, Itoh S. Osako T, et al. Among authors: tosha t. Dalton Trans. 2005 Nov 7;(21):3514-21. doi: 10.1039/b500202h. Epub 2005 Sep 23. Dalton Trans. 2005. PMID: 16234933

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