Chen Y - Search Results

1

Structure-activity relationship among purpurinimides and bacteriopurpurinimides: trifluoromethyl substituent enhanced the photosensitizing efficacy.

Gryshuk A, Chen Y, Goswami LN, Pandey S, Missert JR, Ohulchanskyy T, Potter W, Prasad PN, Oseroff A, Pandey RK. Gryshuk A, et al. Among authors: chen y. J Med Chem. 2007 Apr 19;50(8):1754-67. doi: 10.1021/jm061036q. Epub 2007 Mar 20. J Med Chem. 2007. PMID: 17371002

2

Bacteriopurpurinimides: highly stable and potent photosensitizers for photodynamic therapy.

Chen Y, Graham A, Potter W, Morgan J, Vaughan L, Bellnier DA, Henderson BW, Oseroff A, Dougherty TJ, Pandey RK. Chen Y, et al. J Med Chem. 2002 Jan 17;45(2):255-8. doi: 10.1021/jm010400c. J Med Chem. 2002. PMID: 11784129

3

Structure-activity relationship of new octaethylporphyrin-based benzochlorins as photosensitizers for photodynamic therapy.

Graham A, Li G, Chen Y, Morgan J, Oseroff A, Dougherty TJ, Pandey RK. Graham A, et al. Among authors: chen y. Photochem Photobiol. 2003 May;77(5):561-6. doi: 10.1562/0031-8655(2003)077<0561:sronob>2.0.co;2. Photochem Photobiol. 2003. PMID: 12812301

4

Synthesis, comparative photosensitizing efficacy, human serum albumin (site II) binding ability, and intracellular localization characteristics of novel benzobacteriochlorins derived from vic-dihydroxybacteriochlorins.

Li G, Graham A, Chen Y, Dobhal MP, Morgan J, Zheng G, Kozyrev A, Oseroff A, Dougherty TJ, Pandey RK. Li G, et al. Among authors: chen y. J Med Chem. 2003 Dec 4;46(25):5349-59. doi: 10.1021/jm030341y. J Med Chem. 2003. PMID: 14640543

5

Functionalization of OEP-based benzochlorins to develop carbohydrate-conjugated photosensitizers. Attempt to target beta-galactoside-recognized proteins.

Li G, Pandey SK, Graham A, Dobhal MP, Mehta R, Chen Y, Gryshuk A, Rittenhouse-Olson K, Oseroff A, Pandey RK. Li G, et al. Among authors: chen y. J Org Chem. 2004 Jan 9;69(1):158-72. doi: 10.1021/jo030280b. J Org Chem. 2004. PMID: 14703392

6

Synthesis and photosensitizing efficacy of isomerically pure bacteriopurpurinimides.

Chen Y, Sumlin A, Morgan J, Gryshuk A, Oseroff A, Henderson BW, Dougherty TJ, Pandey RK. Chen Y, et al. J Med Chem. 2004 Sep 23;47(20):4814-7. doi: 10.1021/jm049630s. J Med Chem. 2004. PMID: 15369384

7

Methyl pyropheophorbide-a analogues: potential fluorescent probes for the peripheral-type benzodiazepine receptor. Effect of central metal in photosensitizing efficacy.

Chen Y, Zheng X, Dobhal MP, Gryshuk A, Morgan J, Dougherty TJ, Oseroff A, Pandey RK. Chen Y, et al. J Med Chem. 2005 Jun 2;48(11):3692-5. doi: 10.1021/jm050039k. J Med Chem. 2005. PMID: 15916419

8

Investigation of human serum albumin (HSA) binding specificity of certain photosensitizers related to pyropheophorbide-a and bacteriopurpurinimide by circular dichroism spectroscopy and its correlation with in vivo photosensitizing efficacy.

Chen Y, Miclea R, Srikrishnan T, Balasubramanian S, Dougherty TJ, Pandey RK. Chen Y, et al. Bioorg Med Chem Lett. 2005 Jul 1;15(13):3189-92. doi: 10.1016/j.bmcl.2005.05.019. Bioorg Med Chem Lett. 2005. PMID: 15936945

9

A novel approach to a bifunctional photosensitizer for tumor imaging and phototherapy.

Chen Y, Gryshuk A, Achilefu S, Ohulchansky T, Potter W, Zhong T, Morgan J, Chance B, Prasad PN, Henderson BW, Oseroff A, Pandey RK. Chen Y, et al. Bioconjug Chem. 2005 Sep-Oct;16(5):1264-74. doi: 10.1021/bc050177o. Bioconjug Chem. 2005. PMID: 16173807

10

Multimodality agents for tumor imaging (PET, fluorescence) and photodynamic therapy. A possible "see and treat" approach.

Pandey SK, Gryshuk AL, Sajjad M, Zheng X, Chen Y, Abouzeid MM, Morgan J, Charamisinau I, Nabi HA, Oseroff A, Pandey RK. Pandey SK, et al. Among authors: chen y. J Med Chem. 2005 Oct 6;48(20):6286-95. doi: 10.1021/jm050427m. J Med Chem. 2005. PMID: 16190755

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