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Nonredundant roles for Stat5a/b in directly regulating Foxp3.
Yao Z, Kanno Y, Kerenyi M, Stephens G, Durant L, Watford WT, Laurence A, Robinson GW, Shevach EM, Moriggl R, Hennighausen L, Wu C, O'Shea JJ. Yao Z, et al. Blood. 2007 May 15;109(10):4368-75. doi: 10.1182/blood-2006-11-055756. Epub 2007 Jan 16. Blood. 2007. PMID: 17227828 Free PMC article.
Stat5a/b are essential for normal lymphoid development and differentiation.
Yao Z, Cui Y, Watford WT, Bream JH, Yamaoka K, Hissong BD, Li D, Durum SK, Jiang Q, Bhandoola A, Hennighausen L, O'Shea JJ. Yao Z, et al. Proc Natl Acad Sci U S A. 2006 Jan 24;103(4):1000-5. doi: 10.1073/pnas.0507350103. Epub 2006 Jan 17. Proc Natl Acad Sci U S A. 2006. PMID: 16418296 Free PMC article.
Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation.
Laurence A, Tato CM, Davidson TS, Kanno Y, Chen Z, Yao Z, Blank RB, Meylan F, Siegel R, Hennighausen L, Shevach EM, O'shea JJ. Laurence A, et al. Among authors: yao z. Immunity. 2007 Mar;26(3):371-81. doi: 10.1016/j.immuni.2007.02.009. Immunity. 2007. PMID: 17363300 Free article.
FOXP3 and RORγt: transcriptional regulation of Treg and Th17.
Chen Z, Lin F, Gao Y, Li Z, Zhang J, Xing Y, Deng Z, Yao Z, Tsun A, Li B. Chen Z, et al. Among authors: yao z. Int Immunopharmacol. 2011 May;11(5):536-42. doi: 10.1016/j.intimp.2010.11.008. Epub 2010 Nov 23. Int Immunopharmacol. 2011. PMID: 21081189 Review.
The ubiquitin ligase Stub1 negatively modulates regulatory T cell suppressive activity by promoting degradation of the transcription factor Foxp3.
Chen Z, Barbi J, Bu S, Yang HY, Li Z, Gao Y, Jinasena D, Fu J, Lin F, Chen C, Zhang J, Yu N, Li X, Shan Z, Nie J, Gao Z, Tian H, Li Y, Yao Z, Zheng Y, Park BV, Pan Z, Zhang J, Dang E, Li Z, Wang H, Luo W, Li L, Semenza GL, Zheng SG, Loser K, Tsun A, Greene MI, Pardoll DM, Pan F, Li B. Chen Z, et al. Among authors: yao z. Immunity. 2013 Aug 22;39(2):272-85. doi: 10.1016/j.immuni.2013.08.006. Immunity. 2013. PMID: 23973223 Free PMC article.
6,945 results