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Rapid conditional knock-down-knock-in system for mammalian cells.
Hölzel M, Rohrmoser M, Orban M, Hömig C, Harasim T, Malamoussi A, Gruber-Eber A, Heissmeyer V, Bornkamm G, Eick D. Hölzel M, et al. Among authors: gruber eber a. Nucleic Acids Res. 2007;35(3):e17. doi: 10.1093/nar/gkl1055. Epub 2006 Dec 14. Nucleic Acids Res. 2007. PMID: 17169998 Free PMC article.
Interdependence of Pes1, Bop1, and WDR12 controls nucleolar localization and assembly of the PeBoW complex required for maturation of the 60S ribosomal subunit.
Rohrmoser M, Hölzel M, Grimm T, Malamoussi A, Harasim T, Orban M, Pfisterer I, Gruber-Eber A, Kremmer E, Eick D. Rohrmoser M, et al. Among authors: gruber eber a. Mol Cell Biol. 2007 May;27(10):3682-94. doi: 10.1128/MCB.00172-07. Epub 2007 Mar 12. Mol Cell Biol. 2007. PMID: 17353269 Free PMC article.
Chemotherapeutic drugs inhibit ribosome biogenesis at various levels.
Burger K, Mühl B, Harasim T, Rohrmoser M, Malamoussi A, Orban M, Kellner M, Gruber-Eber A, Kremmer E, Hölzel M, Eick D. Burger K, et al. Among authors: gruber eber a. J Biol Chem. 2010 Apr 16;285(16):12416-25. doi: 10.1074/jbc.M109.074211. Epub 2010 Feb 16. J Biol Chem. 2010. PMID: 20159984 Free PMC article.
4-thiouridine inhibits rRNA synthesis and causes a nucleolar stress response.
Burger K, Mühl B, Kellner M, Rohrmoser M, Gruber-Eber A, Windhager L, Friedel CC, Dölken L, Eick D. Burger K, et al. Among authors: gruber eber a. RNA Biol. 2013 Oct;10(10):1623-30. doi: 10.4161/rna.26214. Epub 2013 Sep 4. RNA Biol. 2013. PMID: 24025460 Free PMC article.
MIR sequences recruit zinc finger protein ZNF768 to expressed genes.
Rohrmoser M, Kluge M, Yahia Y, Gruber-Eber A, Maqbool MA, Forné I, Krebs S, Blum H, Greifenberg AK, Geyer M, Descostes N, Imhof A, Andrau JC, Friedel CC, Eick D. Rohrmoser M, et al. Among authors: gruber eber a. Nucleic Acids Res. 2019 Jan 25;47(2):700-715. doi: 10.1093/nar/gky1148. Nucleic Acids Res. 2019. PMID: 30476274 Free PMC article.