Oostendorp R - Search Results

1

A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis.

Niedernhofer LJ, Garinis GA, Raams A, Lalai AS, Robinson AR, Appeldoorn E, Odijk H, Oostendorp R, Ahmad A, van Leeuwen W, Theil AF, Vermeulen W, van der Horst GT, Meinecke P, Kleijer WJ, Vijg J, Jaspers NG, Hoeijmakers JH. Niedernhofer LJ, et al. Among authors: oostendorp r. Nature. 2006 Dec 21;444(7122):1038-43. doi: 10.1038/nature05456. Nature. 2006. PMID: 17183314

2

Organic anion-transporting polypeptide 1B1 mediates transport of Gimatecan and BNP1350 and can be inhibited by several classic ATP-binding cassette (ABC) B1 and/or ABCG2 inhibitors.

Oostendorp RL, van de Steeg E, van der Kruijssen CM, Beijnen JH, Kenworthy KE, Schinkel AH, Schellens JH. Oostendorp RL, et al. Drug Metab Dispos. 2009 Apr;37(4):917-23. doi: 10.1124/dmd.108.024901. Epub 2009 Jan 12. Drug Metab Dispos. 2009. PMID: 19139163

3

The effect of hydroxyurea on P-glycoprotein/BCRP-mediated transport and CYP3A metabolism of imatinib mesylate.

Oostendorp RL, Marchetti S, Beijnen JH, Mazzanti R, Schellens JH. Oostendorp RL, et al. Cancer Chemother Pharmacol. 2007 May;59(6):855-60. doi: 10.1007/s00280-006-0334-2. Epub 2006 Dec 16. Cancer Chemother Pharmacol. 2007. PMID: 17180388

4

In vitro transport of gimatecan (7-t-butoxyiminomethylcamptothecin) by breast cancer resistance protein, P-glycoprotein, and multidrug resistance protein 2.

Marchetti S, Oostendorp RL, Pluim D, van Eijndhoven M, van Tellingen O, Schinkel AH, Versace R, Beijnen JH, Mazzanti R, Schellens JH. Marchetti S, et al. Among authors: oostendorp rl. Mol Cancer Ther. 2007 Dec;6(12 Pt 1):3307-13. doi: 10.1158/1535-7163.MCT-07-0461. Mol Cancer Ther. 2007. PMID: 18089724

5

The biological and clinical role of drug transporters at the intestinal barrier.

Oostendorp RL, Beijnen JH, Schellens JH. Oostendorp RL, et al. Cancer Treat Rev. 2009 Apr;35(2):137-47. doi: 10.1016/j.ctrv.2008.09.004. Epub 2008 Nov 4. Cancer Treat Rev. 2009. PMID: 18986769 Review.

6

Determination of imatinib mesylate and its main metabolite (CGP74588) in human plasma and murine specimens by ion-pairing reversed-phase high-performance liquid chromatography.

Oostendorp RL, Beijnen JH, Schellens JH, Tellingen Ov. Oostendorp RL, et al. Biomed Chromatogr. 2007 Jul;21(7):747-54. doi: 10.1002/bmc.816. Biomed Chromatogr. 2007. PMID: 17385801

7

Dose-finding and pharmacokinetic study of orally administered indibulin (D-24851) to patients with advanced solid tumors.

Oostendorp RL, Witteveen PO, Schwartz B, Vainchtein LD, Schot M, Nol A, Rosing H, Beijnen JH, Voest EE, Schellens JH. Oostendorp RL, et al. Invest New Drugs. 2010 Apr;28(2):163-70. doi: 10.1007/s10637-009-9244-6. Epub 2009 Apr 30. Invest New Drugs. 2010. PMID: 19404582 Clinical Trial.

8

Bioequivalence study of a new oral topotecan formulation, relative to the current topotecan formulation, in patients with advanced solid tumors.

Oostendorp RL, Loftiss J, Goel S, Smith DA, Dar MM, Witteveen PO, Cohen RB, Lewis LD, Kurian S, Patnaik A, Rosing H, Beijnen JH, Voest EE, Burris H, J. Oostendorp RL, et al. Int J Clin Pharmacol Ther. 2009 Mar;47(3):195-206. doi: 10.5414/cpp47195. Int J Clin Pharmacol Ther. 2009. PMID: 19281729 Clinical Trial.

9

Is rectal administration an alternative route for imatinib?

van Erp NP, Oostendorp RL, Guchelaar HJ, Schellens JH, Gelderblom H. van Erp NP, et al. Cancer Chemother Pharmacol. 2007 Sep;60(4):623-4. doi: 10.1007/s00280-006-0409-0. Epub 2007 Feb 8. Cancer Chemother Pharmacol. 2007. PMID: 17287936 Free article. No abstract available.

10

The effect of P-gp (Mdr1a/1b), BCRP (Bcrp1) and P-gp/BCRP inhibitors on the in vivo absorption, distribution, metabolism and excretion of imatinib.

Oostendorp RL, Buckle T, Beijnen JH, van Tellingen O, Schellens JH. Oostendorp RL, et al. Invest New Drugs. 2009 Feb;27(1):31-40. doi: 10.1007/s10637-008-9138-z. Epub 2008 May 1. Invest New Drugs. 2009. PMID: 18449471

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