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Structure of wild-type Plk-1 kinase domain in complex with a selective DARPin.
Bandeiras TM, Hillig RC, Matias PM, Eberspaecher U, Fanghänel J, Thomaz M, Miranda S, Crusius K, Pütter V, Amstutz P, Gulotti-Georgieva M, Binz HK, Holz C, Schmitz AA, Lang C, Donner P, Egner U, Carrondo MA, Müller-Tiemann B. Bandeiras TM, et al. Among authors: hillig rc. Acta Crystallogr D Biol Crystallogr. 2008 Apr;64(Pt 4):339-53. doi: 10.1107/S0907444907068217. Epub 2008 Mar 19. Acta Crystallogr D Biol Crystallogr. 2008. PMID: 18391401
A structural biology view of target drugability.
Egner U, Hillig RC. Egner U, et al. Among authors: hillig rc. Expert Opin Drug Discov. 2008 Apr;3(4):391-401. doi: 10.1517/17460441.3.4.391. Expert Opin Drug Discov. 2008. PMID: 23489095
Crystallization and molecular-replacement solution of a diagnostic fluorescent dye in complex with a specific Fab fragment.
Hillig RC, Baesler S, Urlinger S, Stark Y, Bauer S, Badock V, Huber M, Bahr I, Schirner M, Licha K. Hillig RC, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Mar 1;63(Pt 3):217-23. doi: 10.1107/S1744309107005957. Epub 2007 Feb 23. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007. PMID: 17329818 Free PMC article.
A Novel NAMPT Inhibitor-Based Antibody-Drug Conjugate Payload Class for Cancer Therapy.
Böhnke N, Berger M, Griebenow N, Rottmann A, Erkelenz M, Hammer S, Berndt S, Günther J, Wengner AM, Stelte-Ludwig B, Mahlert C, Greven S, Dietz L, Jörißen H, Barak N, Bömer U, Hillig RC, Eberspaecher U, Weiske J, Giese A, Mumberg D, Nising CF, Weinmann H, Sommer A. Böhnke N, et al. Among authors: hillig rc. Bioconjug Chem. 2022 Jun 15;33(6):1210-1221. doi: 10.1021/acs.bioconjchem.2c00178. Epub 2022 Jun 3. Bioconjug Chem. 2022. PMID: 35658441 Free PMC article.
Crystal structures of the selenoprotein glutathione peroxidase 4 in its apo form and in complex with the covalently bound inhibitor ML162.
Moosmayer D, Hilpmann A, Hoffmann J, Schnirch L, Zimmermann K, Badock V, Furst L, Eaton JK, Viswanathan VS, Schreiber SL, Gradl S, Hillig RC. Moosmayer D, et al. Among authors: hillig rc. Acta Crystallogr D Struct Biol. 2021 Feb 1;77(Pt 2):237-248. doi: 10.1107/S2059798320016125. Epub 2021 Jan 26. Acta Crystallogr D Struct Biol. 2021. PMID: 33559612 Free PMC article.
35 results