Egner U - Search Results

1

Identifying protein construct variants with increased crystallization propensity--a case study.

Malawski GA, Hillig RC, Monteclaro F, Eberspaecher U, Schmitz AA, Crusius K, Huber M, Egner U, Donner P, Müller-Tiemann B. Malawski GA, et al. Among authors: egner u. Protein Sci. 2006 Dec;15(12):2718-28. doi: 10.1110/ps.062491906. Protein Sci. 2006. PMID: 17132859 Free PMC article.

2

Structural basis for a high affinity inhibitor bound to protein kinase MK2.

Hillig RC, Eberspaecher U, Monteclaro F, Huber M, Nguyen D, Mengel A, Muller-Tiemann B, Egner U. Hillig RC, et al. Among authors: egner u. J Mol Biol. 2007 Jun 8;369(3):735-45. doi: 10.1016/j.jmb.2007.03.004. Epub 2007 Mar 12. J Mol Biol. 2007. PMID: 17449059

3

A structural biology view of target drugability.

Egner U, Hillig RC. Egner U, et al. Expert Opin Drug Discov. 2008 Apr;3(4):391-401. doi: 10.1517/17460441.3.4.391. Expert Opin Drug Discov. 2008. PMID: 23489095

4

Structure of wild-type Plk-1 kinase domain in complex with a selective DARPin.

Bandeiras TM, Hillig RC, Matias PM, Eberspaecher U, Fanghänel J, Thomaz M, Miranda S, Crusius K, Pütter V, Amstutz P, Gulotti-Georgieva M, Binz HK, Holz C, Schmitz AA, Lang C, Donner P, Egner U, Carrondo MA, Müller-Tiemann B. Bandeiras TM, et al. Among authors: egner u. Acta Crystallogr D Biol Crystallogr. 2008 Apr;64(Pt 4):339-53. doi: 10.1107/S0907444907068217. Epub 2008 Mar 19. Acta Crystallogr D Biol Crystallogr. 2008. PMID: 18391401

5

Structural basis for the glucocorticoid response in a mutant human androgen receptor (AR(ccr)) derived from an androgen-independent prostate cancer.

Matias PM, Carrondo MA, Coelho R, Thomaz M, Zhao XY, Wegg A, Crusius K, Egner U, Donner P. Matias PM, et al. Among authors: egner u. J Med Chem. 2002 Mar 28;45(7):1439-46. doi: 10.1021/jm011072j. J Med Chem. 2002. PMID: 11906285

6

Cloning, purification, and crystallization of Escherichia coli cystathionine beta-lyase.

Laber B, Clausen T, Huber R, Messerschmidt A, Egner U, Müller-Fahrnow A, Pohlenz HD. Laber B, et al. Among authors: egner u. FEBS Lett. 1996 Jan 22;379(1):94-6. doi: 10.1016/0014-5793(95)01499-3. FEBS Lett. 1996. PMID: 8566238 Free article.

7

Different ligands-different receptor conformations: modeling of the hER alpha LBD in complex with agonists and antagonists.

Egner U, Heinrich N, Ruff M, Gangloff M, Mueller-Fahrnow A, Wurtz JM. Egner U, et al. Med Res Rev. 2001 Nov;21(6):523-39. doi: 10.1002/med.1024. Med Res Rev. 2001. PMID: 11607933 Review.

8

Ligand-binding domain of estrogen receptors.

Mueller-Fahrnow A, Egner U. Mueller-Fahrnow A, et al. Among authors: egner u. Curr Opin Biotechnol. 1999 Dec;10(6):550-6. doi: 10.1016/s0958-1669(99)00034-8. Curr Opin Biotechnol. 1999. PMID: 10600690 Review.

9

Structural analysis of the GR ligand-binding domain.

Egner U. Egner U. Ernst Schering Res Found Workshop. 2002;(40):341-56. doi: 10.1007/978-3-662-04660-9_19. Ernst Schering Res Found Workshop. 2002. PMID: 12355725 Review. No abstract available.

10

The target discovery process.

Egner U, Krätzschmar J, Kreft B, Pohlenz HD, Schneider M. Egner U, et al. Chembiochem. 2005 Mar;6(3):468-79. doi: 10.1002/cbic.200400158. Chembiochem. 2005. PMID: 15742383 Review.

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