Stevens EB - Search Results

1

The role of sodium channels in neuropathic pain.

Rogers M, Tang L, Madge DJ, Stevens EB. Rogers M, et al. Among authors: stevens eb. Semin Cell Dev Biol. 2006 Oct;17(5):571-81. doi: 10.1016/j.semcdb.2006.10.009. Epub 2006 Oct 28. Semin Cell Dev Biol. 2006. PMID: 17123847 Review.

2

beta 3: an additional auxiliary subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kinetics.

Morgan K, Stevens EB, Shah B, Cox PJ, Dixon AK, Lee K, Pinnock RD, Hughes J, Richardson PJ, Mizuguchi K, Jackson AP. Morgan K, et al. Among authors: stevens eb. Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2308-13. doi: 10.1073/pnas.030362197. Proc Natl Acad Sci U S A. 2000. PMID: 10688874 Free PMC article.

3

beta3, a novel auxiliary subunit for the voltage-gated sodium channel, is expressed preferentially in sensory neurons and is upregulated in the chronic constriction injury model of neuropathic pain.

Shah BS, Stevens EB, Gonzalez MI, Bramwell S, Pinnock RD, Lee K, Dixon AK. Shah BS, et al. Among authors: stevens eb. Eur J Neurosci. 2000 Nov;12(11):3985-90. doi: 10.1046/j.1460-9568.2000.00294.x. Eur J Neurosci. 2000. PMID: 11069594

4

The sodium channel beta-subunit SCN3b modulates the kinetics of SCN5a and is expressed heterogeneously in sheep heart.

Fahmi AI, Patel M, Stevens EB, Fowden AL, John JE 3rd, Lee K, Pinnock R, Morgan K, Jackson AP, Vandenberg JI. Fahmi AI, et al. Among authors: stevens eb. J Physiol. 2001 Dec 15;537(Pt 3):693-700. doi: 10.1111/j.1469-7793.2001.00693.x. J Physiol. 2001. PMID: 11744748 Free PMC article.

5

Developmental expression of the novel voltage-gated sodium channel auxiliary subunit beta3, in rat CNS.

Shah BS, Stevens EB, Pinnock RD, Dixon AK, Lee K. Shah BS, et al. Among authors: stevens eb. J Physiol. 2001 Aug 1;534(Pt 3):763-76. doi: 10.1111/j.1469-7793.2001.t01-1-00763.x. J Physiol. 2001. PMID: 11483707 Free PMC article.

6

Potassium channels: gene family, therapeutic relevance, high-throughput screening technologies and drug discovery.

Ford JW, Stevens EB, Treherne JM, Packer J, Bushfield M. Ford JW, et al. Among authors: stevens eb. Prog Drug Res. 2002;58:133-68. doi: 10.1007/978-3-0348-8183-8_4. Prog Drug Res. 2002. PMID: 12079199 Review.

7

Ion channels as therapeutic targets: a drug discovery perspective.

Bagal SK, Brown AD, Cox PJ, Omoto K, Owen RM, Pryde DC, Sidders B, Skerratt SE, Stevens EB, Storer RI, Swain NA. Bagal SK, et al. Among authors: stevens eb. J Med Chem. 2013 Feb 14;56(3):593-624. doi: 10.1021/jm3011433. Epub 2012 Nov 29. J Med Chem. 2013. PMID: 23121096 Review.

8

Recent advances in targeting ion channels to treat chronic pain.

Stevens EB, Stephens GJ. Stevens EB, et al. Br J Pharmacol. 2018 Jun;175(12):2133-2137. doi: 10.1111/bph.14215. Br J Pharmacol. 2018. PMID: 29878335 Free PMC article.

9

The discovery and optimization of benzimidazoles as selective Na_V1.8 blockers for the treatment of pain.

Brown AD, Bagal SK, Blackwell P, Blakemore DC, Brown B, Bungay PJ, Corless M, Crawforth J, Fengas D, Fenwick DR, Gray V, Kemp M, Klute W, Malet Sanz L, Miller D, Murata Y, Payne CE, Skerratt S, Stevens EB, Warmus JS. Brown AD, et al. Among authors: stevens eb. Bioorg Med Chem. 2019 Jan 1;27(1):230-239. doi: 10.1016/j.bmc.2018.12.002. Epub 2018 Dec 4. Bioorg Med Chem. 2019. PMID: 30538065

10

Bombesin receptors inhibit G protein-coupled inwardly rectifying K+ channels expressed in Xenopus oocytes through a protein kinase C-dependent pathway.

Stevens EB, Shah BS, Pinnock RD, Lee K. Stevens EB, et al. Mol Pharmacol. 1999 Jun;55(6):1020-7. Mol Pharmacol. 1999. PMID: 10347243

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