Madge DJ - Search Results

1

The role of sodium channels in neuropathic pain.

Rogers M, Tang L, Madge DJ, Stevens EB. Rogers M, et al. Among authors: madge dj. Semin Cell Dev Biol. 2006 Oct;17(5):571-81. doi: 10.1016/j.semcdb.2006.10.009. Epub 2006 Oct 28. Semin Cell Dev Biol. 2006. PMID: 17123847 Review.

2

Human electrophysiological and pharmacological properties of XEN-D0101: a novel atrial-selective Kv1.5/IKur inhibitor.

Ford J, Milnes J, Wettwer E, Christ T, Rogers M, Sutton K, Madge D, Virag L, Jost N, Horvath Z, Matschke K, Varro A, Ravens U. Ford J, et al. J Cardiovasc Pharmacol. 2013 May;61(5):408-15. doi: 10.1097/FJC.0b013e31828780eb. J Cardiovasc Pharmacol. 2013. PMID: 23364608 Clinical Trial.

3

Action of clathrodin and analogues on voltage-gated sodium channels.

Peigneur S, Zula A, Zidar N, Chan-Porter F, Kirby R, Madge D, Ilaš J, Kikelj D, Tytgat J. Peigneur S, et al. Mar Drugs. 2014 Apr 4;12(4):2132-43. doi: 10.3390/md12042132. Mar Drugs. 2014. PMID: 24714127 Free PMC article.

4

Substituted 4-phenyl-2-aminoimidazoles and 4-phenyl-4,5-dihydro-2-aminoimidazoles as voltage-gated sodium channel modulators.

Zidar N, Jakopin Ž, Madge DJ, Chan F, Tytgat J, Peigneur S, Dolenc MS, Tomašić T, Ilaš J, Mašič LP, Kikelj D. Zidar N, et al. Among authors: madge dj. Eur J Med Chem. 2014 Mar 3;74:23-30. doi: 10.1016/j.ejmech.2013.12.034. Epub 2014 Jan 3. Eur J Med Chem. 2014. PMID: 24440379

5

Medicinal chemistry of neuronal voltage-gated sodium channel blockers.

Anger T, Madge DJ, Mulla M, Riddall D. Anger T, et al. Among authors: madge dj. J Med Chem. 2001 Jan 18;44(2):115-37. doi: 10.1021/jm000155h. J Med Chem. 2001. PMID: 11170622 Review. No abstract available.

6

Prediction of ion channel activity using binary kernel discrimination.

Willett P, Wilton D, Hartzoulakis B, Tang R, Ford J, Madge D. Willett P, et al. J Chem Inf Model. 2007 Sep-Oct;47(5):1961-6. doi: 10.1021/ci700087v. Epub 2007 Jul 10. J Chem Inf Model. 2007. PMID: 17622131

7

Novel state-dependent voltage-gated sodium channel modulators, based on marine alkaloids from Agelas sponges.

Hodnik Ž, Tomašić T, Mašič LP, Chan F, Kirby RW, Madge DJ, Kikelj D. Hodnik Ž, et al. Among authors: madge dj. Eur J Med Chem. 2013;70:154-64. doi: 10.1016/j.ejmech.2013.07.034. Epub 2013 Aug 11. Eur J Med Chem. 2013. PMID: 24148992

8

New pharmacological approaches to atrial fibrillation.

Milnes JT, Madge DJ, Ford JW. Milnes JT, et al. Among authors: madge dj. Drug Discov Today. 2012 Jul;17(13-14):654-9. doi: 10.1016/j.drudis.2012.02.007. Epub 2012 Feb 20. Drug Discov Today. 2012. PMID: 22370250 Review.

9

Near-thorough QT study as part of a first-in-man study.

Malik M, Hnatkova K, Ford J, Madge D. Malik M, et al. J Clin Pharmacol. 2008 Oct;48(10):1146-57. doi: 10.1177/0091270008323261. Epub 2008 Aug 29. J Clin Pharmacol. 2008. PMID: 18757785 Clinical Trial.

10

Ligand- and structure-based virtual screening for clathrodin-derived human voltage-gated sodium channel modulators.

Tomašić T, Hartzoulakis B, Zidar N, Chan F, Kirby RW, Madge DJ, Peigneur S, Tytgat J, Kikelj D. Tomašić T, et al. Among authors: madge dj. J Chem Inf Model. 2013 Dec 23;53(12):3223-32. doi: 10.1021/ci400505e. Epub 2013 Nov 19. J Chem Inf Model. 2013. PMID: 24215100

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