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Physical and structural basis for the strong interactions of the -ImPy- central pairing motif in the polyamide f-ImPyIm.
Biochemistry. 2006 Nov 14;45(45):13551-65. doi: 10.1021/bi061245c.
Biochemistry. 2006.
PMID: 17087509
Design of a hairpin polyamide, ZT65B, for targeting the inverted CCAAT box (ICB) site in the multidrug resistant (MDR1) gene.
Buchmueller KL, Taherbhai Z, Howard CM, Bailey SL, Nguyen B, O'Hare C, Hochhauser D, Hartley JA, Wilson WD, Lee M.
Buchmueller KL, et al.
Chembiochem. 2005 Dec;6(12):2305-11. doi: 10.1002/cbic.200500179.
Chembiochem. 2005.
PMID: 16254941
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Synthesis and biophysical evaluation of minor-groove binding C-terminus modified pyrrole and imidazole triamide analogs of distamycin.
Brown T, Taherbhai Z, Sexton J, Sutterfield A, Turlington M, Jones J, Stallings L, Stewart M, Buchmueller K, Mackay H, O'hare C, Kluza J, Nguyen B, Wilson D, Lee M, Hartley JA.
Brown T, et al.
Bioorg Med Chem. 2007 Jan 1;15(1):474-83. doi: 10.1016/j.bmc.2006.09.037. Epub 2006 Oct 10.
Bioorg Med Chem. 2007.
PMID: 17035029
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Modulation of topoisomerase IIalpha expression by a DNA sequence-specific polyamide.
Hochhauser D, Kotecha M, O'hare C, Morris PJ, Hartley JM, Taherbhai Z, Harris D, Forni C, Mantovani R, Lee M, Hartley JA.
Hochhauser D, et al.
Mol Cancer Ther. 2007 Jan;6(1):346-54. doi: 10.1158/1535-7163.MCT-06-0503.
Mol Cancer Ther. 2007.
PMID: 17237293
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