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Immunization of Rhesus monkeys with a SialylTn-mAb17-1A conjugate vaccine co-formulated with QS-21 induces a temporary systemic cytokine release and NK cytotoxicity against tumor cells.
Kircheis R, Siegl P, Grunt S, Halanek N, Loibner H, Mudde GC, Nechansky A. Kircheis R, et al. Among authors: halanek n. Cancer Immunol Immunother. 2007 Jun;56(6):863-73. doi: 10.1007/s00262-006-0231-x. Epub 2006 Sep 29. Cancer Immunol Immunother. 2007. PMID: 17009044 Free PMC article.
Complement dependent cytotoxicity (CDC) activity of a humanized anti Lewis-Y antibody: FACS-based assay versus the 'classical' radioactive method -- qualification, comparison and application of the FACS-based approach.
Nechansky A, Szolar OH, Siegl P, Zinoecker I, Halanek N, Wiederkum S, Kircheis R. Nechansky A, et al. Among authors: halanek n. J Pharm Biomed Anal. 2009 May 1;49(4):1014-20. doi: 10.1016/j.jpba.2009.01.029. Epub 2009 Feb 4. J Pharm Biomed Anal. 2009. PMID: 19250790
The biological effects of syngeneic and allogeneic cytokine-expressing prophylactic whole cell vaccines and the influence of irradiation in a murine melanoma model.
Labarthe MC, Halanek N, Birchall L, Russell N, Desel C, Todryk S, Peters MJ, Lucas A, Falkenberg FW, Dalgleish AG, Whelan M, Ward SJ. Labarthe MC, et al. Among authors: halanek n. Cancer Immunol Immunother. 2006 Mar;55(3):277-88. doi: 10.1007/s00262-005-0061-2. Epub 2005 Sep 13. Cancer Immunol Immunother. 2006. PMID: 16158275 Free PMC article.
CD40 ligation for immunotherapy of solid tumours.
Todryk SM, Tutt AL, Green MH, Smallwood JA, Halanek N, Dalgleish AG, Glennie MJ. Todryk SM, et al. Among authors: halanek n. J Immunol Methods. 2001 Feb 1;248(1-2):139-47. doi: 10.1016/s0022-1759(00)00349-5. J Immunol Methods. 2001. PMID: 11223075