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306 results

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Minimizing the risk of reporting false positives in large-scale RNAi screens.
Echeverri CJ, Beachy PA, Baum B, Boutros M, Buchholz F, Chanda SK, Downward J, Ellenberg J, Fraser AG, Hacohen N, Hahn WC, Jackson AL, Kiger A, Linsley PS, Lum L, Ma Y, Mathey-Prévôt B, Root DE, Sabatini DM, Taipale J, Perrimon N, Bernards R. Echeverri CJ, et al. Among authors: linsley ps. Nat Methods. 2006 Oct;3(10):777-9. doi: 10.1038/nmeth1006-777. Nat Methods. 2006. PMID: 16990807
Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studies.
Kittler R, Surendranath V, Heninger AK, Slabicki M, Theis M, Putz G, Franke K, Caldarelli A, Grabner H, Kozak K, Wagner J, Rees E, Korn B, Frenzel C, Sachse C, Sönnichsen B, Guo J, Schelter J, Burchard J, Linsley PS, Jackson AL, Habermann B, Buchholz F. Kittler R, et al. Among authors: linsley ps. Nat Methods. 2007 Apr;4(4):337-44. doi: 10.1038/nmeth1025. Epub 2007 Mar 11. Nat Methods. 2007. PMID: 17351622
Hidden reach of the micromanagers.
Linsley PS, Jackson AL. Linsley PS, et al. BMC Biol. 2010 May 11;8:53. doi: 10.1186/1741-7007-8-53. BMC Biol. 2010. PMID: 20529236 Free PMC article. Review.
Expression profiling reveals off-target gene regulation by RNAi.
Jackson AL, Bartz SR, Schelter J, Kobayashi SV, Burchard J, Mao M, Li B, Cavet G, Linsley PS. Jackson AL, et al. Among authors: linsley ps. Nat Biotechnol. 2003 Jun;21(6):635-7. doi: 10.1038/nbt831. Epub 2003 May 18. Nat Biotechnol. 2003. PMID: 12754523
A large-scale RNAi screen in human cells identifies new components of the p53 pathway.
Berns K, Hijmans EM, Mullenders J, Brummelkamp TR, Velds A, Heimerikx M, Kerkhoven RM, Madiredjo M, Nijkamp W, Weigelt B, Agami R, Ge W, Cavet G, Linsley PS, Beijersbergen RL, Bernards R. Berns K, et al. Among authors: linsley ps. Nature. 2004 Mar 25;428(6981):431-7. doi: 10.1038/nature02371. Nature. 2004. PMID: 15042092
A microRNA component of the p53 tumour suppressor network.
He L, He X, Lim LP, de Stanchina E, Xuan Z, Liang Y, Xue W, Zender L, Magnus J, Ridzon D, Jackson AL, Linsley PS, Chen C, Lowe SW, Cleary MA, Hannon GJ. He L, et al. Among authors: linsley ps. Nature. 2007 Jun 28;447(7148):1130-4. doi: 10.1038/nature05939. Epub 2007 Jun 6. Nature. 2007. PMID: 17554337 Free PMC article.
Gene expression profiling predicts clinical outcome of breast cancer.
van 't Veer LJ, Dai H, van de Vijver MJ, He YD, Hart AA, Mao M, Peterse HL, van der Kooy K, Marton MJ, Witteveen AT, Schreiber GJ, Kerkhoven RM, Roberts C, Linsley PS, Bernards R, Friend SH. van 't Veer LJ, et al. Among authors: linsley ps. Nature. 2002 Jan 31;415(6871):530-6. doi: 10.1038/415530a. Nature. 2002. PMID: 11823860
306 results