Bosco DA - Search Results

1

Small molecule oxidation products trigger disease-associated protein misfolding.

Bieschke J, Zhang Q, Bosco DA, Lerner RA, Powers ET, Wentworth P Jr, Kelly JW. Bieschke J, et al. Among authors: bosco da. Acc Chem Res. 2006 Sep;39(9):611-9. doi: 10.1021/ar0500766. Acc Chem Res. 2006. PMID: 16981677 Review.

2

Elevated levels of oxidized cholesterol metabolites in Lewy body disease brains accelerate alpha-synuclein fibrilization.

Bosco DA, Fowler DM, Zhang Q, Nieva J, Powers ET, Wentworth P Jr, Lerner RA, Kelly JW. Bosco DA, et al. Nat Chem Biol. 2006 May;2(5):249-53. doi: 10.1038/nchembio782. Epub 2006 Mar 26. Nat Chem Biol. 2006. PMID: 16565714

3

Localized thermodynamic coupling between hydrogen bonding and microenvironment polarity substantially stabilizes proteins.

Gao J, Bosco DA, Powers ET, Kelly JW. Gao J, et al. Among authors: bosco da. Nat Struct Mol Biol. 2009 Jul;16(7):684-90. doi: 10.1038/nsmb.1610. Epub 2009 Jun 14. Nat Struct Mol Biol. 2009. PMID: 19525973 Free PMC article.

4

Dissecting the microscopic steps of the cyclophilin A enzymatic cycle on the biological HIV-1 capsid substrate by NMR.

Bosco DA, Eisenmesser EZ, Clarkson MW, Wolf-Watz M, Labeikovsky W, Millet O, Kern D. Bosco DA, et al. J Mol Biol. 2010 Nov 12;403(5):723-38. doi: 10.1016/j.jmb.2010.08.001. Epub 2010 Aug 12. J Mol Biol. 2010. PMID: 20708627

5

Structure and dynamics of pin1 during catalysis by NMR.

Labeikovsky W, Eisenmesser EZ, Bosco DA, Kern D. Labeikovsky W, et al. Among authors: bosco da. J Mol Biol. 2007 Apr 13;367(5):1370-81. doi: 10.1016/j.jmb.2007.01.049. Epub 2007 Jan 24. J Mol Biol. 2007. PMID: 17316687 Free PMC article.

6

Intrinsic dynamics of an enzyme underlies catalysis.

Eisenmesser EZ, Millet O, Labeikovsky W, Korzhnev DM, Wolf-Watz M, Bosco DA, Skalicky JJ, Kay LE, Kern D. Eisenmesser EZ, et al. Among authors: bosco da. Nature. 2005 Nov 3;438(7064):117-21. doi: 10.1038/nature04105. Nature. 2005. PMID: 16267559

7

Enzyme dynamics during catalysis.

Eisenmesser EZ, Bosco DA, Akke M, Kern D. Eisenmesser EZ, et al. Among authors: bosco da. Science. 2002 Feb 22;295(5559):1520-3. doi: 10.1126/science.1066176. Science. 2002. PMID: 11859194

8

Catalysis of cis/trans isomerization in native HIV-1 capsid by human cyclophilin A.

Bosco DA, Eisenmesser EZ, Pochapsky S, Sundquist WI, Kern D. Bosco DA, et al. Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5247-52. doi: 10.1073/pnas.082100499. Epub 2002 Apr 2. Proc Natl Acad Sci U S A. 2002. PMID: 11929983 Free PMC article.

9

Catalysis and binding of cyclophilin A with different HIV-1 capsid constructs.

Bosco DA, Kern D. Bosco DA, et al. Biochemistry. 2004 May 25;43(20):6110-9. doi: 10.1021/bi049841z. Biochemistry. 2004. PMID: 15147195

10

A yeast model of FUS/TLS-dependent cytotoxicity.

Ju S, Tardiff DF, Han H, Divya K, Zhong Q, Maquat LE, Bosco DA, Hayward LJ, Brown RH Jr, Lindquist S, Ringe D, Petsko GA. Ju S, et al. Among authors: bosco da. PLoS Biol. 2011 Apr;9(4):e1001052. doi: 10.1371/journal.pbio.1001052. Epub 2011 Apr 26. PLoS Biol. 2011. PMID: 21541368 Free PMC article.

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