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Efficacy of novel rifamycin derivatives against rifamycin-sensitive and -resistant Staphylococcus aureus isolates in murine models of infection.
Antimicrob Agents Chemother. 2006 Nov;50(11):3658-64. doi: 10.1128/AAC.01087-05. Epub 2006 Aug 28.
Antimicrob Agents Chemother. 2006.
PMID: 16940074
Free PMC article.
Novel, non-colonizing, single-strain live biotherapeutic product ADS024 protects against Clostridioides difficile infection challenge in vivo.
Murphy CK, O'Donnell MM, Hegarty JW, Schulz S, Hill C, Ross RP, Rea MC, Farquhar R, Chesnel L.
Murphy CK, et al.
World J Gastrointest Pathophysiol. 2023 Aug 24;14(4):71-85. doi: 10.4291/wjgp.v14.i4.71.
World J Gastrointest Pathophysiol. 2023.
PMID: 37727283
Free PMC article.
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A novel dual NLRP1 and NLRP3 inflammasome inhibitor for the treatment of inflammatory diseases.
Docherty CA, Fernando AJ, Rosli S, Lam M, Dolle RE, Navia MA, Farquhar R, La France D, Tate MD, Murphy CK, Rossi AG, Mansell A.
Docherty CA, et al.
Clin Transl Immunology. 2023 Jun 22;12(6):e1455. doi: 10.1002/cti2.1455. eCollection 2023.
Clin Transl Immunology. 2023.
PMID: 37360982
Free PMC article.
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Development of ADS051, an oral, gut-restricted, small molecule neutrophil modulator for the treatment of neutrophil-mediated inflammatory diseases.
Murphy CK, Dixit B, Oleson FB, Dolle RE, Farquhar R, McCormick BA.
Murphy CK, et al.
FEBS Open Bio. 2023 Aug;13(8):1434-1446. doi: 10.1002/2211-5463.13668. Epub 2023 Jul 10.
FEBS Open Bio. 2023.
PMID: 37392453
Free PMC article.
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Identification of ADS024, a newly characterized strain of Bacillus velezensis with direct Clostridiodes difficile killing and toxin degradation bio-activities.
O'Donnell MM, Hegarty JW, Healy B, Schulz S, Walsh CJ, Hill C, Ross RP, Rea MC, Farquhar R, Chesnel L.
O'Donnell MM, et al.
Sci Rep. 2022 Jun 3;12(1):9283. doi: 10.1038/s41598-022-13248-4.
Sci Rep. 2022.
PMID: 35662257
Free PMC article.
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