Widmann C - Search Results

1

Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype.

Heurteaux C, Lucas G, Guy N, El Yacoubi M, Thümmler S, Peng XD, Noble F, Blondeau N, Widmann C, Borsotto M, Gobbi G, Vaugeois JM, Debonnel G, Lazdunski M. Heurteaux C, et al. Among authors: widmann c. Nat Neurosci. 2006 Sep;9(9):1134-41. doi: 10.1038/nn1749. Epub 2006 Aug 13. Nat Neurosci. 2006. PMID: 16906152

2

Spadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: a new concept in the antidepressant drug design.

Mazella J, Pétrault O, Lucas G, Deval E, Béraud-Dufour S, Gandin C, El-Yacoubi M, Widmann C, Guyon A, Chevet E, Taouji S, Conductier G, Corinus A, Coppola T, Gobbi G, Nahon JL, Heurteaux C, Borsotto M. Mazella J, et al. Among authors: widmann c. PLoS Biol. 2010 Apr 13;8(4):e1000355. doi: 10.1371/journal.pbio.1000355. PLoS Biol. 2010. PMID: 20405001 Free PMC article.

3

TREK-1, a K+ channel involved in neuroprotection and general anesthesia.

Heurteaux C, Guy N, Laigle C, Blondeau N, Duprat F, Mazzuca M, Lang-Lazdunski L, Widmann C, Zanzouri M, Romey G, Lazdunski M. Heurteaux C, et al. Among authors: widmann c. EMBO J. 2004 Jul 7;23(13):2684-95. doi: 10.1038/sj.emboj.7600234. Epub 2004 Jun 3. EMBO J. 2004. PMID: 15175651 Free PMC article.

4

Activation of the nuclear factor-kappaB is a key event in brain tolerance.

Blondeau N, Widmann C, Lazdunski M, Heurteaux C. Blondeau N, et al. Among authors: widmann c. J Neurosci. 2001 Jul 1;21(13):4668-77. doi: 10.1523/JNEUROSCI.21-13-04668.2001. J Neurosci. 2001. PMID: 11425894 Free PMC article.

5

Polyunsaturated fatty acids induce ischemic and epileptic tolerance.

Blondeau N, Widmann C, Lazdunski M, Heurteaux C. Blondeau N, et al. Among authors: widmann c. Neuroscience. 2002;109(2):231-41. doi: 10.1016/s0306-4522(01)00473-0. Neuroscience. 2002. PMID: 11801360

6

Spadin as a new antidepressant: absence of TREK-1-related side effects.

Moha Ou Maati H, Veyssiere J, Labbal F, Coppola T, Gandin C, Widmann C, Mazella J, Heurteaux C, Borsotto M. Moha Ou Maati H, et al. Among authors: widmann c. Neuropharmacology. 2012 Jan;62(1):278-88. doi: 10.1016/j.neuropharm.2011.07.019. Epub 2011 Jul 22. Neuropharmacology. 2012. PMID: 21807005

7

A potent protective role of lysophospholipids against global cerebral ischemia and glutamate excitotoxicity in neuronal cultures.

Blondeau N, Lauritzen I, Widmann C, Lazdunski M, Heurteaux C. Blondeau N, et al. Among authors: widmann c. J Cereb Blood Flow Metab. 2002 Jul;22(7):821-34. doi: 10.1097/00004647-200207000-00007. J Cereb Blood Flow Metab. 2002. PMID: 12142567

8

MLC901 Favors Angiogenesis and Associated Recovery after Ischemic Stroke in Mice.

Gandin C, Widmann C, Lazdunski M, Heurteaux C. Gandin C, et al. Among authors: widmann c. Cerebrovasc Dis. 2016;42(1-2):139-54. doi: 10.1159/000444810. Epub 2016 Apr 22. Cerebrovasc Dis. 2016. PMID: 27099921 Free article.

9

K+ channel openers prevent global ischemia-induced expression of c-fos, c-jun, heat shock protein, and amyloid beta-protein precursor genes and neuronal death in rat hippocampus.

Heurteaux C, Bertaina V, Widmann C, Lazdunski M. Heurteaux C, et al. Among authors: widmann c. Proc Natl Acad Sci U S A. 1993 Oct 15;90(20):9431-5. doi: 10.1073/pnas.90.20.9431. Proc Natl Acad Sci U S A. 1993. PMID: 8415718 Free PMC article.

10

Polyunsaturated fatty acids are potent neuroprotectors.

Lauritzen I, Blondeau N, Heurteaux C, Widmann C, Romey G, Lazdunski M. Lauritzen I, et al. Among authors: widmann c. EMBO J. 2000 Apr 17;19(8):1784-93. doi: 10.1093/emboj/19.8.1784. EMBO J. 2000. PMID: 10775263 Free PMC article.

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