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Differences in signaling pathways by IL-1beta and IL-18.
Lee JK, Kim SH, Lewis EC, Azam T, Reznikov LL, Dinarello CA. Lee JK, et al. Among authors: lewis ec. Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8815-20. doi: 10.1073/pnas.0402800101. Epub 2004 May 25. Proc Natl Acad Sci U S A. 2004. PMID: 15161979 Free PMC article.
Cisplatin-induced acute renal failure is associated with an increase in the cytokines interleukin (IL)-1beta, IL-18, IL-6, and neutrophil infiltration in the kidney.
Faubel S, Lewis EC, Reznikov L, Ljubanovic D, Hoke TS, Somerset H, Oh DJ, Lu L, Klein CL, Dinarello CA, Edelstein CL. Faubel S, et al. Among authors: lewis ec. J Pharmacol Exp Ther. 2007 Jul;322(1):8-15. doi: 10.1124/jpet.107.119792. Epub 2007 Mar 30. J Pharmacol Exp Ther. 2007. PMID: 17400889
α1-Antitrypsin therapy downregulates toll-like receptor-induced IL-1β responses in monocytes and myeloid dendritic cells and may improve islet function in recently diagnosed patients with type 1 diabetes.
Gottlieb PA, Alkanani AK, Michels AW, Lewis EC, Shapiro L, Dinarello CA, Zipris D. Gottlieb PA, et al. Among authors: lewis ec. J Clin Endocrinol Metab. 2014 Aug;99(8):E1418-26. doi: 10.1210/jc.2013-3864. Epub 2014 Feb 14. J Clin Endocrinol Metab. 2014. PMID: 24527714 Free PMC article. Clinical Trial.
IL-37 protects against obesity-induced inflammation and insulin resistance.
Ballak DB, van Diepen JA, Moschen AR, Jansen HJ, Hijmans A, Groenhof GJ, Leenders F, Bufler P, Boekschoten MV, Müller M, Kersten S, Li S, Kim S, Eini H, Lewis EC, Joosten LA, Tilg H, Netea MG, Tack CJ, Dinarello CA, Stienstra R. Ballak DB, et al. Among authors: lewis ec. Nat Commun. 2014 Sep 3;5:4711. doi: 10.1038/ncomms5711. Nat Commun. 2014. PMID: 25182023 Free article.
151 results