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Cannabinoid receptors as therapeutic targets.
Pavlopoulos S, Thakur GA, Nikas SP, Makriyannis A. Pavlopoulos S, et al. Among authors: makriyannis a. Curr Pharm Des. 2006;12(14):1751-69. doi: 10.2174/138161206776873743. Curr Pharm Des. 2006. PMID: 16712486 Review.
CB1 cannabinoid receptor ligands.
Thakur GA, Nikas SP, Makriyannis A. Thakur GA, et al. Among authors: makriyannis a. Mini Rev Med Chem. 2005 Jul;5(7):631-40. doi: 10.2174/1389557054368772. Mini Rev Med Chem. 2005. PMID: 16026309 Review.
Cannabinergic ligands.
Palmer SL, Thakur GA, Makriyannis A. Palmer SL, et al. Among authors: makriyannis a. Chem Phys Lipids. 2002 Dec 31;121(1-2):3-19. doi: 10.1016/s0009-3084(02)00143-3. Chem Phys Lipids. 2002. PMID: 12505686 Review.
Enantiomeric resolution of a novel chiral cannabinoid receptor ligand.
Thakur GA, Palmer SL, Harrington PE, Stergiades IA, Tius MA, Makriyannis A. Thakur GA, et al. Among authors: makriyannis a. J Biochem Biophys Methods. 2002 Dec 31;54(1-3):415-22. doi: 10.1016/s0165-022x(02)00144-6. J Biochem Biophys Methods. 2002. PMID: 12543516
Structural requirements for cannabinoid receptor probes.
Thakur GA, Nikas SP, Li C, Makriyannis A. Thakur GA, et al. Among authors: makriyannis a. Handb Exp Pharmacol. 2005;(168):209-46. doi: 10.1007/3-540-26573-2_7. Handb Exp Pharmacol. 2005. PMID: 16596776 Review.
Behavioral effects of the novel cannabinoid full agonist AM 411.
McLaughlin PJ, Lu D, Winston KM, Thakur G, Swezey LA, Makriyannis A, Salamone JD. McLaughlin PJ, et al. Among authors: makriyannis a. Pharmacol Biochem Behav. 2005 May;81(1):78-88. doi: 10.1016/j.pbb.2005.02.005. Epub 2005 Apr 21. Pharmacol Biochem Behav. 2005. PMID: 15894067
(-)-7'-Isothiocyanato-11-hydroxy-1',1'-dimethylheptylhexahydrocannabinol (AM841), a high-affinity electrophilic ligand, interacts covalently with a cysteine in helix six and activates the CB1 cannabinoid receptor.
Picone RP, Khanolkar AD, Xu W, Ayotte LA, Thakur GA, Hurst DP, Abood ME, Reggio PH, Fournier DJ, Makriyannis A. Picone RP, et al. Among authors: makriyannis a. Mol Pharmacol. 2005 Dec;68(6):1623-35. doi: 10.1124/mol.105.014407. Epub 2005 Sep 12. Mol Pharmacol. 2005. PMID: 16157695
Natural cannabinoids: templates for drug discovery.
Thakur GA, Duclos RI Jr, Makriyannis A. Thakur GA, et al. Among authors: makriyannis a. Life Sci. 2005 Dec 22;78(5):454-66. doi: 10.1016/j.lfs.2005.09.014. Epub 2005 Oct 19. Life Sci. 2005. PMID: 16242157 Review.
Methods for the synthesis of cannabinergic ligands.
Thakur GA, Nikas SP, Duclos RI Jr, Makriyannis A. Thakur GA, et al. Among authors: makriyannis a. Methods Mol Med. 2006;123:113-48. doi: 10.1385/1-59259-999-0:113. Methods Mol Med. 2006. PMID: 16506405
514 results