Nelson SD - Search Results

1

Cytosolic heat shock proteins and heme oxygenase-1 are preferentially induced in response to specific and localized intramitochondrial damage by tetrafluoroethylcysteine.

Ho HK, Jia Y, Coe KJ, Gao Q, Doneanu CE, Hu Z, Bammler TK, Beyer RP, Fausto N, Bruschi SA, Nelson SD. Ho HK, et al. Among authors: nelson sd. Biochem Pharmacol. 2006 Jun 28;72(1):80-90. doi: 10.1016/j.bcp.2006.03.019. Epub 2006 Mar 29. Biochem Pharmacol. 2006. PMID: 16678137

2

BCL-xL overexpression effectively protects against tetrafluoroethylcysteine-induced intramitochondrial damage and cell death.

Ho HK, Hu ZH, Tzung SP, Hockenbery DM, Fausto N, Nelson SD, Bruschi SA. Ho HK, et al. Among authors: nelson sd. Biochem Pharmacol. 2005 Jan 1;69(1):147-57. doi: 10.1016/j.bcp.2004.08.030. Biochem Pharmacol. 2005. PMID: 15588723

3

Nrf2 activation involves an oxidative-stress independent pathway in tetrafluoroethylcysteine-induced cytotoxicity.

Ho HK, White CC, Fernandez C, Fausto N, Kavanagh TJ, Nelson SD, Bruschi SA. Ho HK, et al. Among authors: nelson sd. Toxicol Sci. 2005 Aug;86(2):354-64. doi: 10.1093/toxsci/kfi205. Epub 2005 May 18. Toxicol Sci. 2005. PMID: 15901913

4

Mitochondrial aconitase modification, functional inhibition, and evidence for a supramolecular complex of the TCA cycle by the renal toxicant S-(1,1,2,2-tetrafluoroethyl)-L-cysteine.

James EA, Gygi SP, Adams ML, Pierce RH, Fausto N, Aebersold RH, Nelson SD, Bruschi SA. James EA, et al. Among authors: nelson sd. Biochemistry. 2002 May 28;41(21):6789-97. doi: 10.1021/bi020038j. Biochemistry. 2002. PMID: 12022883

5

Cell culture model for acetaminophen-induced hepatocyte death in vivo.

Pierce RH, Franklin CC, Campbell JS, Tonge RP, Chen W, Fausto N, Nelson SD, Bruschi SA. Pierce RH, et al. Among authors: nelson sd. Biochem Pharmacol. 2002 Aug 1;64(3):413-24. doi: 10.1016/s0006-2952(02)01180-2. Biochem Pharmacol. 2002. PMID: 12147292

6

Comparison of the cytotoxicity of the nitroaromatic drug flutamide to its cyano analogue in the hepatocyte cell line TAMH: evidence for complex I inhibition and mitochondrial dysfunction using toxicogenomic screening.

Coe KJ, Jia Y, Ho HK, Rademacher P, Bammler TK, Beyer RP, Farin FM, Woodke L, Plymate SR, Fausto N, Nelson SD. Coe KJ, et al. Among authors: nelson sd. Chem Res Toxicol. 2007 Sep;20(9):1277-90. doi: 10.1021/tx7001349. Epub 2007 Aug 17. Chem Res Toxicol. 2007. PMID: 17702527 Free PMC article.

7

Differential regulation of mitogen-activated protein kinase pathways by acetaminophen and its nonhepatotoxic regioisomer 3'-hydroxyacetanilide in TAMH cells.

Stamper BD, Bammler TK, Beyer RP, Farin FM, Nelson SD. Stamper BD, et al. Among authors: nelson sd. Toxicol Sci. 2010 Jul;116(1):164-73. doi: 10.1093/toxsci/kfq100. Epub 2010 Apr 2. Toxicol Sci. 2010. PMID: 20363829 Free PMC article.

8

Enhanced acetaminophen hepatotoxicity in transgenic mice overexpressing BCL-2.

Adams ML, Pierce RH, Vail ME, White CC, Tonge RP, Kavanagh TJ, Fausto N, Nelson SD, Bruschi SA. Adams ML, et al. Among authors: nelson sd. Mol Pharmacol. 2001 Nov;60(5):907-15. doi: 10.1124/mol.60.5.907. Mol Pharmacol. 2001. PMID: 11641418

9

Probing the CYP3A4 active site by cysteine scanning mutagenesis and photoaffinity labeling.

Wen B, Doneanu CE, Lampe JN, Roberts AG, Atkins WM, Nelson SD. Wen B, et al. Among authors: nelson sd. Arch Biochem Biophys. 2005 Dec 15;444(2):100-11. doi: 10.1016/j.abb.2005.09.010. Epub 2005 Oct 21. Arch Biochem Biophys. 2005. PMID: 16289363

10

Pro-CrossLink. Software tool for protein cross-linking and mass spectrometry.

Gao Q, Xue S, Doneanu CE, Shaffer SA, Goodlett DR, Nelson SD. Gao Q, et al. Among authors: nelson sd. Anal Chem. 2006 Apr 1;78(7):2145-9. doi: 10.1021/ac051339c. Anal Chem. 2006. PMID: 16579592

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