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Stabilization and humanization of a single-chain Fv antibody fragment specific for human lymphocyte antigen CD19 by designed point mutations and CDR-grafting onto a human framework.
Kügler M, Stein C, Schwenkert M, Saul D, Vockentanz L, Huber T, Wetzel SK, Scholz O, Plückthun A, Honegger A, Fey GH. Kügler M, et al. Among authors: saul d. Protein Eng Des Sel. 2009 Mar;22(3):135-47. doi: 10.1093/protein/gzn079. Epub 2009 Feb 1. Protein Eng Des Sel. 2009. PMID: 19188138 Free article.
A recombinant trispecific single-chain Fv derivative directed against CD123 and CD33 mediates effective elimination of acute myeloid leukaemia cells by dual targeting.
Kügler M, Stein C, Kellner C, Mentz K, Saul D, Schwenkert M, Schubert I, Singer H, Oduncu F, Stockmeyer B, Mackensen A, Fey GH. Kügler M, et al. Among authors: saul d. Br J Haematol. 2010 Sep;150(5):574-86. doi: 10.1111/j.1365-2141.2010.08300.x. Epub 2010 Jul 16. Br J Haematol. 2010. PMID: 20636437 Free article.
221 results